DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-23

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001022281.1	Gene:	nas-23 / 3565992	WormBaseID:	WBGene00003542	Length:	537	Species:	Caenorhabditis elegans

Alignment Length:	246	Identity:	84/246 - (34%)
Similarity:	128/246 - (52%)	Gaps:	29/246 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 SDTNIWEHCGLFEGDIMLHRELLRNGLLNERL-------------TWPEAA----VPFYIDPQ-D 118
            ||.|..:...||:|||.|..|.|.| ::.|:|             .:|:..    |||.:... .
Worm    74 SDLNRSKRDLLFQGDIHLSFEHLSN-IVREQLDHSRTKRTAFRNAMYPKTIWLPNVPFELHGSLS 137

  Fly   119 FNANQTMVILKAFKEYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGR--RSGGQVLNLNTPK 181
            ..:..::|...||.|.|  ||:.|:. ...:|.:||:.|...||||:|||  ..|.|:||:.| .
Worm   138 AKSRSSLVAAMAFWEKH--TCVAFKK-RTSEKVYLLMSGQEEGCWSTVGRDEAQGAQILNIGT-G 198

  Fly   182 CVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSV 246
            |...|:..||:.||||.:|:||..:||.||:|....|...:.::|....:.::..:|.:||..||
Worm   199 CEMFGITSHEIAHALGLFHEQSRYDRDNYVQIVKSRIAQTNFYDFAVVGKKNMETYGQKYDIGSV 263

  Fly   247 MHYSSRAFSKNGKATI--EPLDPYASLGQRRGLSDKDVSKLNEMY--EQDC 293
            |||....||.:|..:|  :.::...::||.||.|..||:|:|..|  |::|
Worm   264 MHYRPTEFSLDGGNSIIAKDVNMQNTMGQFRGPSFIDVAKINRHYNCEKNC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	70/201 (35%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	66/183 (36%)
nas-23	NP_001022281.1	Astacin	122..310	CDD:279708	67/191 (35%)
		ZnMc_astacin_like	128..308	CDD:239807	66/183 (36%)
		CUB	384..454	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910