DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6696 and nas-39

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001360030.1	Gene:	nas-39 / 3565986	WormBaseID:	WBGene00003555	Length:	928	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	73/223 - (32%)
Similarity:	117/223 - (52%)	Gaps:	17/223 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 GDIMLHRELLRNGLLNERLT------WPEAAVPFYIDPQDFNANQTMVILKAFKEYHDRTCIRFR 143
            ||:...|....||.::...|      |||..:||.| ..:|:.....:.|:|.:.:.:.||:.|.
Worm    31 GDVRFRRYYRNNGRVSRAATAKKERIWPEGIIPFVI-ASNFSGEHQHLFLRAMRHWENFTCVSFV 94

  Fly   144 PYEQGDKHWLLIKGNYSGCWSSVGRR-SGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATER 207
            |.:...||::....:..||.|.|||| .|.|.:::. ..|...|:|||||.|.:||:|:.:..:|
Worm    95 PRQPHHKHYITFTVDKCGCCSYVGRRGEGPQAISIG-KNCDKFGIVVHELGHVVGFWHEHTRPDR 158

  Fly   208 DEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNG-KATIEPLDPYA-- 269
            |.||.|.:::|..|..:||.|.....:.:.|..||:.|:|||:...||:.. ..||.| .|.:
Worm   159 DMYVDIFYKSIQTGQDYNFEKSKPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILP-KPNSGF 222

  Fly   270 --SLGQRRGLSDKDVSKLNEMYEQDCSE 295
              .:|||..||:.|:.:..::|:  |:|
Worm   223 RLEIGQRVQLSEGDIRQTKKLYK--CAE 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	67/202 (33%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	61/184 (33%)
nas-39	NP_001360030.1	ZnMc_BMP1_TLD	48..247	CDD:239808	66/203 (33%)
		CUB	268..343	CDD:214483
		CUB	359..474	CDD:238001
		FXa_inhibition	480..515	CDD:373209
		CUB	519..622	CDD:366096
		FXa_inhibition	629..664	CDD:373209
		CUB	669..780	CDD:238001
		CUB	782..898	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810