DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and Tll1

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_033416.2	Gene:	Tll1 / 21892	MGIID:	106923	Length:	1013	Species:	Mus musculus

Alignment Length:	211	Identity:	67/211 - (31%)
Similarity:	106/211 - (50%)	Gaps:	29/211 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 ERLTWPEAAVPFYIDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQGDKH-WLLIKGNYSGCWS 164
            ||: ||...:| |:...:|..:|..:..:|.:.:...||:.|.  |:.|:. :::......||.|
Mouse   154 ERI-WPGGVIP-YVIGGNFTGSQRAMFKQAMRHWEKHTCVTFT--ERSDEESYIVFTYRPCGCCS 214

  Fly   165 SVGRRSGG-QVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNK 228
            .||||..| |.:::. ..|...|:|||||.|.:||:|:.:..:||.:|.|..|||..|..:||.|
Mouse   215 YVGRRGNGPQAISIG-KNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLK 278

  Fly   229 YARTHITNFGVEYDYQSVMHYSSRAFSK-------------NGKATIEPLDPYASLGQRRGLSDK 280
            .....:.:.|..||:.|:|||:...||:             ||   |.|     ::|||..||..
Mouse   279 MEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNG---IRP-----AIGQRTRLSKG 335

  Fly   281 DVSKLNEMYE-QDCSE 295
            |:::..::|. ..|.|
Mouse   336 DIAQARKLYRCPACGE 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	64/206 (31%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	60/193 (31%)
Tll1	NP_033416.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..150
		ZnMc_BMP1_TLD	148..347	CDD:239808	65/205 (32%)
		Astacin	155..348	CDD:279708	64/205 (31%)
		CUB	349..458	CDD:278839	2/3 (67%)
		CUB	462..571	CDD:278839
		FXa_inhibition	582..614	CDD:291342
		CUB	618..727	CDD:278839
		FXa_inhibition	734..769	CDD:291342
		CUB	774..883	CDD:278839
		CUB	887..1000	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810