DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-33

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_509086.2	Gene:	nas-33 / 186987	WormBaseID:	WBGene00003551	Length:	644	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	78/226 - (34%)
Similarity:	119/226 - (52%)	Gaps:	22/226 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 LFEGDIML----HRELLRNGLLNER------LTWPEAAVPFYIDPQDFNANQTMVILKAFKEYHD 136
            :||.|:.|    ..::.:||...:|      .|| ...:|:..  .|.:.|....|....:.|..
Worm   169 MFESDMALTVSQMNKVAQNGFRVKRKMNLNGTTW-SRNIPYRF--LDTDGNWQSQITNGLRHYER 230

  Fly   137 RTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQ 201
            .|||||.....|..:.:..||  .||:|||||..|.|.:::. ..|.|.|::.||:.|||||:|:
Worm   231 NTCIRFSLNGGGSDYLVFSKG--EGCYSSVGRLGGPQEISIG-DGCETLGIITHEVGHALGFWHE 292

  Fly   202 QSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKA-TIEPL 265
            |:..|||.||:||.:|.::|....|:|.:.:.:..:.:.|||.|||||..::|||:... |:||:
Worm   293 QARPERDSYVRINRQNAINGLEGQFDKRSWSEVNEYSLPYDYGSVMHYGPKSFSKSSTMNTVEPV 357

  Fly   266 DP--YASLGQRRGLSDKDVSKLNEMYEQDCS 294
            ||  ..::|.|...|..|:..||..:   ||
Worm   358 DPAFINTIGNRVEPSFLDLKLLNTAF---CS 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	71/194 (37%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	67/181 (37%)
nas-33	NP_509086.2	Astacin	200..386	CDD:279708	71/195 (36%)
		ZnMc_astacin_like	203..381	CDD:239807	66/182 (36%)
		CUB	442..527	CDD:294042
		TSP1	553..595	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6774
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870