DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-31

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001023994.1	Gene:	nas-31 / 186493	WormBaseID:	WBGene00003549	Length:	611	Species:	Caenorhabditis elegans

Alignment Length:	333	Identity:	95/333 - (28%)
Similarity:	140/333 - (42%)	Gaps:	81/333 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ATLEASTPATRKALLRARPAVPPAAR-WGANMQMLRRHNSPAFNFWTEDSDTN------------ 75
            |.||.:.|.|.  |.|.|.|:....: |.|.:|.:     ||.|:  :::.||
Worm    43 AELEKTFPRTN--LSRMRNALKSLRQNWSAKLQAM-----PARNY--QNAGTNQENGATEQQKPL 98

  Fly    76 -----------------IWEHCG----LFEGDIMLHRELL------------------RNGLLNE 101
                             :.:..|    |::||::|..:.:                  |.....:
Worm    99 REKPRDRVKMEGDTLHQVNKAAGLNDILYQGDMVLTDDQIATILEARDETTVSTASRARRQAYRD 163

  Fly   102 R----LTWPEAAVPFYIDPQDFNANQTMVILKAFKE----YHDRTCIRFRPYEQGDKHWLLIKGN 158
            |    .|| .::|.:|.|     ...|..|:|||::    :.:.|||.............:.||
Worm   164 RYYPSTTW-GSSVYYYYD-----RTATPKIVKAFEQAVAFWQNVTCINIMQSSTAINRIRVFKG- 221

  Fly   159 YSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHA 223
             .||:|.|||.||.|.|:|.| .|...|...|||.|||||:|.||..:||.|:.||:.||...:.
Worm   222 -QGCYSYVGRISGVQDLSLGT-GCEEFGTAAHELGHALGFFHTQSRYDRDNYISINYANIDPSYV 284

  Fly   224 HNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKATIEPLD-PYASLGQRRGLSDKDVSKLNE 287
            ..|:|.......|:|:.|||.|:|.|.:.:.|.|.|||:...| .|........:...|:|.:||
Worm   285 EQFDKETSNTNFNYGMPYDYGSIMQYGATSASSNDKATMIARDTEYQDTMGSDFVGFYDISMMNE 349

  Fly   288 MYEQDCSE 295
            .|:  |.|
Worm   350 HYK--CKE 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	70/195 (36%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	66/183 (36%)
nas-31	NP_001023994.1	Astacin	169..355	CDD:279708	70/196 (36%)
		ZnMc_astacin_like	175..351	CDD:239807	66/183 (36%)
		ShKT	532..564	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010