DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-29

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_494953.3	Gene:	nas-29 / 186488	WormBaseID:	WBGene00003547	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	83/257 - (32%)
Similarity:	119/257 - (46%)	Gaps:	52/257 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 LFEGDIML--------------HRELLR--------NGLLNERLTWPEAAVPFYID---PQD--- 118
            |||||:.:              :|:.::        ||...:| |..:|    |:|   |..
Worm    89 LFEGDMAISYKQLSMIVNGSTEYRKAIKSRRRGNKINGESTDR-TKRQA----YLDNNYPATIWK 148

  Fly   119 ------FNANQTMV----ILKAFKEYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGR--RSG 171
                  |:.:.|.:    ||||...::..|||.|.| ....|.:||..||..||||:|||  ..|
Worm   149 NGVAFMFHESLTPIAKTAILKAVHFWYRETCIEFHP-RTFQKEYLLFIGNDDGCWSTVGRDASQG 212

  Fly   172 GQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITN 236
            .||:::.. .|...||..|||.||||.:|:||..:|||.|..|...:......||.|.:...::.
Worm   213 KQVVSIGN-GCEHFGVTSHELAHALGIFHEQSRFDRDESVVFNPRVVERDLLFNFAKISPRQMST 276

  Fly   237 FGVEYDYQSVMHYSSRAFSK-NGKATIEPLDP--YASLGQRRGLSDKDVSKLNEMYEQDCSE 295
            :|:.||..|||||:...||. ....|:..:|.  ..::||..|.|..||..:|:.|:  |.|
Worm   277 YGLPYDIGSVMHYTPTEFSNIPSIPTLAAIDTNLQQTMGQLEGPSFVDVHIMNQHYQ--CQE 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	73/211 (35%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	69/199 (35%)
nas-29	NP_494953.3	Astacin	145..336	CDD:279708	68/194 (35%)
		ZnMc_astacin_like	148..332	CDD:239807	66/185 (36%)
		CUB	404..491	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920