DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-12

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_501871.2	Gene:	nas-12 / 182848	WormBaseID:	WBGene00003531	Length:	384	Species:	Caenorhabditis elegans

Alignment Length:	268	Identity:	70/268 - (26%)
Similarity:	125/268 - (46%)	Gaps:	41/268 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 EASTPATRKALLRARPAVPPAARWGANMQMLRRHNSPAFNFWTEDSDTNIWEHCGLFEGDIMLHR 91
            |..|.|.::..:.....:.||       |::|..||       :|||.:|              |
Worm    35 ELITEANKEHTVFGDMLLTPA-------QLIRYENS-------KDSDLSI--------------R 71

  Fly    92 ELLRNGLLNERLTWPEAAVPFYIDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQGDKHWLLIK 156
            .:...|....|  |....||:.|.|| ::..|..:::.:.:.:...:|.:|  .|:..::..|..
Worm    72 GVSIKGSSMNR--WSNNIVPYVISPQ-YSPAQKQILVSSLRYFERVSCFKF--VERTTQNDYLFI 131

  Fly   157 GNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDG 221
            ....||:|.||:..|.|.|:| ...|:...::.||::||:||.|:....:||.::::::.|::.|
Worm   132 VPLDGCYSYVGKIGGRQTLSL-AADCIADYIIWHEMMHAIGFEHEHQRPDRDSFIRVDYANVIPG 195

  Fly   222 HAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGK------ATIEPLDPYASLGQRRGLSDK 280
            ...||:|...:|: .:...||::|:|||...||.:...      ||:.||.|..:|......:..
Worm   196 QMINFDKLKTSHV-EYPDIYDFKSIMHYDGYAFGRVDTARRVRLATMTPLKPGVTLEDNMKFTAT 259

  Fly   281 DVSKLNEM 288
            |:.|||.:
Worm   260 DIEKLNRL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	54/191 (28%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	53/185 (29%)
nas-12	NP_501871.2	Astacin	81..272	CDD:279708	55/194 (28%)
		ZnMc_astacin_like	85..267	CDD:239807	53/186 (28%)
		ShK	286..325	CDD:279838
		ShK	347..384	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920