DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-7

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_495552.2	Gene:	nas-7 / 182368	WormBaseID:	WBGene00003526	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	85/207 - (41%)
Similarity:	127/207 - (61%)	Gaps:	3/207 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 FEGDIMLHRELLRNGLLNERLTWPEAAVPFYIDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQ 147
            |:.||.|.|...|||:......||.|.:|:.|.|. ::.::..::.||.|:||::|||||.|.:.
Worm    67 FKSDIRLPRRHKRNGVSRAAKLWPNARIPYAISPH-YSPHERALLAKAVKQYHEKTCIRFVPRQT 130

  Fly   148 GDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVK 212
            |:..:|.| |...||:|.|||.||.|||:|:. .|:.:..::||::|.:||||:....:||.::.
Worm   131 GEPDYLFI-GKVDGCFSEVGRTSGVQVLSLDN-GCMEYATIIHEMMHVVGFYHEHERWDRDNFID 193

  Fly   213 INWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKATIEPLDPYASLGQRRGL 277
            |.|:||..|....|.|...:..:.:|..|||:|::||.|.||||||..|:.|....|::|..|..
Worm   194 IIWQNIDRGALDQFGKVDLSKTSYYGQPYDYKSILHYDSLAFSKNGFPTMLPKVKSATIGNARDF 258

  Fly   278 SDKDVSKLNEMY 289
            ||.|:||:|.||
Worm   259 SDVDISKINRMY 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	77/186 (41%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	72/178 (40%)
nas-7	NP_495552.2	Astacin	87..274	CDD:279708	77/187 (41%)
		ZnMc_astacin_like	91..270	CDD:239807	73/181 (40%)
		ShK	347..382	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I2703
Isobase	1	0.950	-	0	Normalized mean entropy	S6774
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		mtm4854
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.920