DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-6

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001040902.1	Gene:	nas-6 / 181796	WormBaseID:	WBGene00003525	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	85/224 - (37%)
Similarity:	131/224 - (58%)	Gaps:	15/224 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 WEHCGLFEGDI---------MLHRELLRNGLLNERLTWPEAAVPFYIDPQDFNANQTMVILKAFK 132
            |::.|.|:|||         :....:|.|.|.|::|||....:|:.:|.. |:.|:..::.|||.
Worm    44 WQNSGKFQGDIDGVDPNLLKLPEGPVLFNALKNKQLTWEGGVIPYEMDTA-FSPNEIKILEKAFD 107

  Fly   133 EYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALG 197
            .|...|||||...|....:..::||  .||:|.|||..|.|.::|.. .|..|.::||||:|::|
Worm   108 SYRRTTCIRFEKREGQTDYLNIVKG--YGCYSQVGRTGGKQEISLGR-GCFFHEIIVHELMHSVG 169

  Fly   198 FYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKATI 262
            |:|:.|..:||:::||||:|||.|....|:|.:.......|..|||:|:|||.|.|||:||:.||
Worm   170 FWHEHSRADRDDHIKINWDNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTI 234

  Fly   263 EPLDPYAS--LGQRRGLSDKDVSKLNEMY 289
            |.::...:  :|....||..|:.|:|::|
Worm   235 ETVENGFTQVIGTAMDLSPLDIVKINKLY 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	74/188 (39%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	71/180 (39%)
nas-6	NP_001040902.1	Astacin	80..265	CDD:279708	74/188 (39%)
		ZnMc_astacin_like	83..263	CDD:239807	71/183 (39%)
		ShK	299..334	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020