DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-10

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001257126.1	Gene:	nas-10 / 181287	WormBaseID:	WBGene00003529	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	77/256 - (30%)
Similarity:	114/256 - (44%)	Gaps:	52/256 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 EHCGLFEGDIMLHRELLRNGLLNE------------------RLT----------WPEAA-VPFY 113
            |..|:|:.|::| .|...|.:|||                  |.:          ||..: :|:.
Worm   251 EDNGVFDKDLLL-TETQANFMLNELGKGGEGAIPMPGSAKAKRASIFFEQNLIQKWPSTSPIPYT 314

  Fly   114 IDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQGDKHWLLIKGNY---------SGC-WSSVGR 168
            .|....|.:|..| ..|..|...:|||||:.:....      |||:         |.| .|.:||
Worm   315 FDSSLDNLDQNDV-RGAISEIEQKTCIRFKYFASPP------KGNHINYQKVNSPSFCGLSYIGR 372

  Fly   169 RSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTH 233
            ......:.|:.......|:.|||.:||||..||....:||:::|::|.||.......|.......
Worm   373 VEPANPVYLSFQCGNGRGIAVHETMHALGVNHQHLRMDRDKHIKVDWSNINPQQYDAFVVADSKL 437

  Fly   234 ITNFGVEYDYQSVMHYSSRAFSKN-GKATIEPL-DPYAS---LGQRRGLSDKDVSKLNEMY 289
            .|.:||:|.|.|:|||::...:.| .|.|:.|| :..|:   ||||..:|:.||..||:||
Worm   438 YTTYGVKYAYDSIMHYNAYTGAVNIAKPTMIPLVNQQANIGLLGQRAKMSNADVEILNKMY 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	66/212 (31%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	62/193 (32%)
nas-10	NP_001257126.1	Astacin	303..501	CDD:396122	66/203 (33%)
nas-10	NP_001257126.1	ShK	503..540	CDD:396228
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020