DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-15

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_508154.2	Gene:	nas-15 / 180426	WormBaseID:	WBGene00003534	Length:	571	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	88/243 - (36%)
Similarity:	133/243 - (54%)	Gaps:	27/243 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 DSDTNIWEHCGL-----FEGDIMLHR------ELLRNG-------------LLNERLTWPEAAVP 111
            |:..:||:...:     |||||....      ||..||             :.|....|||..:|
Worm    65 DNGDDIWDSDAMYSKDRFEGDIANDNLNASTAELFANGGSGKSEDGKWYNAIKNRLQLWPEGRIP 129

  Fly   112 FYIDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLN 176
            :.|..| :::....:|..:.:||...||||:.|.|..|.:::.|..: .||:|.||:..|.|.|:
Worm   130 YTISSQ-YSSYSRSLIAASMQEYASHTCIRWVPKEAADVNYVHIYPD-RGCYSMVGKMGGKQSLS 192

  Fly   177 LNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEY 241
            |.: .|:..|:::|||:||:||:|:||.|:||:::.|.|.||..|....|.||....|.:.|..|
Worm   193 LGS-GCIQKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQGQFEKYGHGTIQSLGTGY 256

  Fly   242 DYQSVMHYSSRAFSKNGKATIEPLDPYASLGQRRGLSDKDVSKLNEMY 289
            ||.|:|||.::|||:||:.|:.|....|::|||.|.|..|..|:|.:|
Worm   257 DYGSIMHYGTKAFSRNGQPTMIPKKNGATIGQRNGFSKVDKFKINTLY 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	75/186 (40%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	71/178 (40%)
nas-15	NP_508154.2	Astacin	121..308	CDD:279708	75/187 (40%)
		ZnMc_astacin_like	126..304	CDD:239807	71/180 (39%)
		ShKT	354..388	CDD:214586
		ShK	436..471	CDD:279838
		Gag_MA	<472..531	CDD:279482
		ShK	535..571	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I2703
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		mtm4854
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.970