DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and nas-38

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001359993.1	Gene:	nas-38 / 180407	WormBaseID:	WBGene00003554	Length:	727	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	87/334 - (26%)
Similarity:	135/334 - (40%)	Gaps:	86/334 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CFWSALALALSATLEASTPATRKALLRARPAVPPAARWGANMQMLRRHNS-------PAFNFWTE 70
            ||...|..:.:|.:   ..|::|.|.|.:..:...|         .|||:       ..|:....
Worm    15 CFCCLLIFSSAARV---PKASKKHLARVKQLLNDEA---------ERHNTLIQSDSVTVFDDIQR 67

  Fly    71 DSDTNIWEHCGL--------FEGDIML------------------HRELLRNGLLNERLTW-PEA 108
            :.:|.: .|..|        |:||:.|                  .|::.||.|..:   | ...
Worm    68 NPNTGV-HHDELAVNNADEYFQGDVDLSEQQVKIIEDQFTQGKREKRKIGRNPLYKK---WDTRG 128

  Fly   109 AVPF-YIDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQG----DKHWLLIKGNYSGCWSSVGR 168
            .:.| |.:...|...|.  |..|...:...||:||   |:|    |:......|   ||.|.|||
Worm   129 PISFDYAESIPFQTRQK--IRSAMLLWQQHTCLRF---EEGGPNVDRLEFFDGG---GCSSFVGR 185

  Fly   169 RSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTH 233
            ..|.|.::::||.|...|::.||:.||||.:|:|:..:::.::.||:.||.....:||......|
Worm   186 VGGTQGISISTPGCDVVGIISHEIGHALGIFHEQARPDQERHIAINYNNIPLSRWNNFQAVGENH 250

  Fly   234 ITNFGVEYDYQSVMHYSSRAFSKNGKATIEPLDPY------------ASLGQRRGLSDKDVSKLN 286
            ...:.:.||..|||||....|:.         |||            :::|||.|.|..|...:|
Worm   251 AETYNLPYDTGSVMHYGPYGFAS---------DPYTPTIRTLERVQQSTIGQRAGPSFLDYQAIN 306

  Fly   287 EMYEQDCSE 295
            ..|  .|:|
Worm   307 MAY--GCTE 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	62/208 (30%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	59/195 (30%)
nas-38	NP_001359993.1	Astacin	122..313	CDD:366617	62/212 (29%)
		CUB	367..466	CDD:214483
		TSP1	613..658	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920