DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and Mep1a

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_032611.2	Gene:	Mep1a / 17287	MGIID:	96963	Length:	760	Species:	Mus musculus

Alignment Length:	243	Identity:	86/243 - (35%)
Similarity:	132/243 - (54%)	Gaps:	23/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 DSDTNIWEH-----------CGLFEGDIMLHRELLRNGLLNERLTWPEAAVPFYIDPQDFNANQT 124
            |.||::.|.           ..||:|||:|.|  .||.:.:....| :..:| ||...:...|..
Mouse    44 DHDTDVGEQKDIFEINLAAGLNLFQGDILLPR--TRNAMRDPSSRW-KLPIP-YILADNLELNAK 104

  Fly   125 MVILKAFKEYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVV 189
            ..||.||:.:..::|:.|:||| |:..:::.: ..|||||.:|.:..||.:::. ..|.....:.
Mouse   105 GAILHAFEMFRLKSCVDFKPYE-GESSYIIFQ-KLSGCWSMIGDQQVGQNISIG-EGCDFKATIE 166

  Fly   190 HELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAF 254
            ||:||||||:|:||.|:||:||.|.|:.|:..:.||||.|....||:....|||:|:|||...:|
Mouse   167 HEILHALGFFHEQSRTDRDDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSF 231

  Fly   255 SKNGK-ATIEPLDPYAS--LGQRRGLSDKDVSKLNEMYEQDCSEDYLL 299
            :||.. .||....|..:  :||....|..|:.:||.||  :|:..:.|
Mouse   232 NKNESIPTITTKIPEFNTIIGQLPDFSAIDLIRLNRMY--NCTATHTL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	72/193 (37%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	68/181 (38%)
Mep1a	NP_032611.2	ZnMc	46..271	CDD:381785	83/233 (36%)
		MAM	281..444	CDD:366209
		MATH	443..607	CDD:351761
		EGF	688..722	CDD:333761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	149	1.000	Domainoid score	I4395
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6774
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8881
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.860