DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and astl

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_031755136.1	Gene:	astl / 101730245	XenbaseID:	XB-GENE-5769376	Length:	972	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	94/251 - (37%)
Similarity:	143/251 - (56%)	Gaps:	38/251 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 GLFEGDIMLHRELLRNGLLNERLT-WPE----AAVPFYIDP--QDFNANQTMVILKAFKEYHDRT 138
            ||.||||:..:..:|.  .:.|.. ||:    ..:|:.:..  :.|:.|   :|||||::....|
Frog    53 GLMEGDIVKEKRSIRT--FSARFAKWPKINGSVIIPYTLSSSYESFDRN---IILKAFRDLQAST 112

  Fly   139 CIRF--RPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLN-----LNTPKCVTHGVVVHELLHAL 196
            |:||  |..|   :.::.|:... ||:|||||..|.|:::     |.|.|  ..|:.:|||:|..
Frog   113 CLRFVERTTE---RDYIAIEPAI-GCFSSVGRVGGMQLVSLAFECLRTDK--GKGIALHELMHVA 171

  Fly   197 GFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKAT 261
            ||:|:.|..:||:|:.|.|:.||.|:..||.|||   .||..|:|:.||::||...||||:|:||
Frog   172 GFWHEHSRADRDDYIWIIWDEILIGYEKNFCKYA---TTNMLVKYELQSILHYPRSAFSKSGQAT 233

  Fly   262 IEPLDPYA--SLGQRRGLSDKDVSKLNEMYEQDCSEDYLLNFDRFGNYIDELLDYF 315
            |.|..||:  .:|||..||..|:.::|::|  .||: |..:.|.     |:.|:||
Frog   234 INPKYPYSKIEIGQREKLSASDILRVNKLY--SCSQ-YTSSDDD-----DDELNYF 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	79/206 (38%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	75/189 (40%)
astl	XP_031755136.1	ZnMc_astacin_like	84..263	CDD:239807	75/190 (39%)
astl	XP_031755136.1	MAM	817..971	CDD:99706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.160