DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and astl3a.3

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_031746774.1	Gene:	astl3a.3 / 100498584	XenbaseID:	XB-GENE-22069675	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	280	Identity:	107/280 - (38%)
Similarity:	149/280 - (53%)	Gaps:	18/280 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LEASTPATRKALLRARPAVPPAARWGANMQMLRRHNSPAFNFWTEDSDTNIWEHCGLFEGDIMLH 90
            |||...:..|..|.....|.     |..|.:|.: .|.:.:.:|:.|..|.......::|||:
Frog    45 LEALGKSAEKDALATEGTVR-----GMEMPVLGK-KSGSVDVFTQISKVNRGIRVPTYQGDIL-- 101

  Fly    91 RELLRNGLLNERLTWPEAAVPFYIDPQDFNANQTMVILKAFK----EYHDRTCIRFRPYEQGDKH 151
            |...|:.:......||::.....|.|.:|::|.:...|..||    ||...||:||.|.......
Frog   102 RPKGRSAMNCTECLWPKSTDGTVIVPYNFSSNYSADQLALFKSTMQEYESLTCVRFVPRANETDF 166

  Fly   152 WLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWE 216
            ..::..|  ||.|.:|:..|.|.:.|::..|:..|::.|||.|||||||:||.::||:||.|:.|
Frog   167 LSIVSDN--GCASFLGKVGGDQTVQLDSYGCIYRGIIQHELNHALGFYHEQSRSDRDDYVTIHTE 229

  Fly   217 NILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKATIEPL-DPYASLGQRRGLSDK 280
            ||:.|:..||||   ....|.|:||||.||||||..||||||..||.|. ||...:|||.|||..
Frog   230 NIIPGYEGNFNK---ADSNNLGLEYDYSSVMHYSGDAFSKNGNLTIVPKPDPTVPIGQRDGLSIL 291

  Fly   281 DVSKLNEMYEQDCSEDYLLN 300
            ||||:|.:|:.|...:.|.|
Frog   292 DVSKINRLYQCDVCSNLLSN 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	87/195 (45%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	83/183 (45%)
astl3a.3	XP_031746774.1	ZnMc_hatching_enzyme	121..302	CDD:239810	84/185 (45%)
		CUB	306..414	CDD:238001	2/6 (33%)
		CUB	419..527	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4121
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060