DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6696 and astl2f

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_002934133.3	Gene:	astl2f / 100495416	XenbaseID:	XB-GENE-22069764	Length:	624	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	90/246 - (36%)
Similarity:	130/246 - (52%)	Gaps:	25/246 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 DSDTNIWEHCGLFEGDIMLHRELLRNGLLN-ERLTWPEAA-----VPFYIDPQDFNANQTMVILK 129
            :.|||:    .|.:|||:   |.|.....| ....||.|.     ||:.| ...|:.::..:|..
Frog   175 NKDTNV----PLVQGDIL---EKLGRSTTNCTSCLWPRATSGLVNVPYTI-ASVFDDSEQELIQG 231

  Fly   130 AFKEYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLH 194
            |..|....:||||:.............||  |||||||:..|.|.::::...|::||::.||.||
Frog   232 ALNELMTLSCIRFKARTIETDFLSFQSGN--GCWSSVGKTGGSQEVSVSKSGCMSHGIIQHETLH 294

  Fly   195 ALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKN-G 258
            ||||.|:...::||.||.|.::.|.:|...:|.|   .:..|.|::|||.|||||....|:.. |
Frog   295 ALGFIHEHCRSDRDNYVDIIYKYISEGDRSSFTK---VNSNNLGLQYDYSSVMHYGRFTFTNTPG 356

  Fly   259 KATIEPL-DPYASLGQRRGLSDKDVSKLNEMYEQD-CSEDYLLNFDRFGNY 307
            :|||.|. |....:|||.|:|..||:|||::|..: ||.  ||: |..|.:
Frog   357 QATIIPKPDLSVPIGQRYGVSSLDVAKLNKLYNCNICSN--LLS-DTSGTF 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	75/198 (38%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	70/180 (39%)
astl2f	XP_002934133.3	ZnMc	209..390	CDD:412141	71/186 (38%)
		CUB	394..504	CDD:238001	5/14 (36%)
		CUB	507..621	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.150