DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and astl2g

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_002934115.1	Gene:	astl2g / 100491886	XenbaseID:	XB-GENE-22069768	Length:	505	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	105/296 - (35%)
Similarity:	145/296 - (48%)	Gaps:	41/296 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SALIVPGLI-CFWSALALALSATLEASTPATRKALLRARPAVPPAARWGANMQMLRRHNSPAFNF 67
            |.|||..|: |.       |.|.||.......|..:....|.|...                 :.
Frog     6 SCLIVASLMQCI-------LGAPLEIYFEEANKIAVSQEEAKPEPK-----------------DV 46

  Fly    68 WTEDSDTNIWEHCGLFEGDIMLHRELLRNGLL--NERLTWPEA----AVPFYIDPQDFNANQTMV 126
            :|..|:||......|.|.||::..:  ||.:.  .:...|..:    .||:.|. .:|:|.:..|
Frog    47 FTIISETNKGVKKLLHESDIVVSVD--RNAMKCDGDTCRWKTSDGIVRVPYTIS-ANFSATEVSV 108

  Fly   127 ILKAFKEYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHE 191
            |:.|.:::...||:.|.|......:..:|..  |||||.||:..|.|.::||...||..|.|.||
Frog   109 IVDAMQDFATLTCVNFVPRTVEPDYLQIIPD--SGCWSYVGKTGGAQEVSLNQGGCVGKGTVQHE 171

  Fly   192 LLHALGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSK 256
            |.|||||||:||.::||.||.|...||:.....||:||   :..|.|.||||.|||||...||:|
Frog   172 LNHALGFYHEQSRSDRDNYVNILTGNIIPASIGNFDKY---NTNNLGQEYDYSSVMHYGRNAFAK 233

  Fly   257 N-GKATIEPL-DPYASLGQRRGLSDKDVSKLNEMYE 290
            . |..||.|. :|...:|||.|||:.|:||:|::|:
Frog   234 QPGLDTIVPKPNPNVPIGQRYGLSNLDISKINQLYQ 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	82/193 (42%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	80/180 (44%)
astl2g	XP_002934115.1	Astacin	83..272	CDD:279708	82/193 (42%)
		ZnMc_hatching_enzyme	88..270	CDD:239810	81/188 (43%)
		CUB	270..384	CDD:238001	105/296 (35%)
		CUB	387..497	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4121
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.070