DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and astl3c

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_002937470.2	Gene:	astl3c / 100491451	XenbaseID:	XB-GENE-22069695	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	215	Identity:	86/215 - (40%)
Similarity:	130/215 - (60%)	Gaps:	16/215 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 GDIMLHRELLRNGLLNERLTWPEAA-----VPFYIDPQDFNANQTMVILKAFKEYHDRTCIRFRP 144
            |||:::  :.|:...::.| ||::|     || ||...:::|::..:...|.:|:...||:||.|
Frog    77 GDILIN--IGRSATSSDYL-WPKSADGTVVVP-YIFSYNYSADELTLFKTAMQEFETLTCVRFVP 137

  Fly   145 YEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDE 209
             :...:.:|.|..| .||.|.|||..|||.:.|.:..|::.||:.|||.|||||||:...::||:
Frog   138 -KTIQRDFLNIVSN-GGCLSMVGRNGGGQKVELASYGCMSRGVIQHELNHALGFYHEHMRSDRDD 200

  Fly   210 YVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFS-KNGKATIEPL-DPYASLG 272
            ||.|..|||:..:.:.|:| .:|:  |.|:.|||.||||||...|| ...|:||.|. ||...:|
Frog   201 YVTIITENIIPSYENYFSK-RKTN--NMGIIYDYNSVMHYSRNTFSISPDKSTIVPKPDPSIPIG 262

  Fly   273 QRRGLSDKDVSKLNEMYEQD 292
            ||.|||..|:.|:.::|:.|
Frog   263 QRDGLSILDILKIKKLYQCD 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	81/196 (41%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	76/180 (42%)
astl3c	XP_002937470.2	ZnMc	99..281	CDD:381785	77/187 (41%)
		CUB	290..393	CDD:366096
		CUB	398..508	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4121
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.070