DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and astl3b.4

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_031746772.1	Gene:	astl3b.4 / 100491283	XenbaseID:	XB-GENE-22069691	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	110/288 - (38%)
Similarity:	151/288 - (52%)	Gaps:	27/288 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LALALSATLEASTPATRKALLRARPAVPPAARWGANMQMLRRHNSPAFNFWTEDSDTNIWEHCGL 82
            |..||..:.|....|| :..:|..|.:              ...|.:.:.:|:.|..|.......
Frog    44 LLKALGKSAEKDALAT-EGTVREMPVL--------------GKKSGSVDVFTQISKVNRGISVPT 93

  Fly    83 FEGDIMLHRELLRNGLLNERLTWPEAAVPFYIDPQDFNAN----QTMVILKAFKEYHDRTCIRFR 143
            :||||:  |...|:.:......||::.....|.|.:|::|    |..:...|.:||...||:||.
Frog    94 YEGDIL--RPEGRSAMNCTECLWPKSTDGTVIVPYNFSSNYSADQLALFKSAMQEYESLTCVRFV 156

  Fly   144 PYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERD 208
            |.........:|.|  |||.|.:|:..|.|.:.|.:..|:..|::.|||.|||||||:||.::||
Frog   157 PRANETAFLNIISG--SGCVSFLGKLGGAQTVQLASYGCIYRGIIQHELNHALGFYHEQSRSDRD 219

  Fly   209 EYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKATIEPL-DPYASLG 272
            :||.|:.||||.|:..|||| |.|:  |.|:||||.|||||...||||||..||.|. ||...:|
Frog   220 DYVTIHTENILPGYEGNFNK-ANTN--NLGLEYDYSSVMHYPGDAFSKNGNLTIVPKPDPTVPIG 281

  Fly   273 QRRGLSDKDVSKLNEMYEQDCSEDYLLN 300
            ||.|||..||||:|.:|:.|...:.|.|
Frog   282 QRDGLSILDVSKINRLYQCDVCSNLLSN 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	90/195 (46%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	86/183 (47%)
astl3b.4	XP_031746772.1	ZnMc_hatching_enzyme	119..300	CDD:239810	87/185 (47%)
		CUB	304..412	CDD:238001	2/6 (33%)
		CUB	417..525	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010