DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and mep1ba

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001070089.2	Gene:	mep1ba / 100151009	ZFINID:	ZDB-GENE-041014-209	Length:	677	Species:	Danio rerio

Alignment Length:	235	Identity:	98/235 - (41%)
Similarity:	136/235 - (57%)	Gaps:	13/235 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 SDTNIWE-----HCGLFEGDIMLHRELLRNGLLNERLTWPEAAVPFYIDPQDFNANQTMVILKAF 131
            :|.:|:|     ...|.||||::.....||.:|.|:..|| ..||:::| .....|...||||||
Zfish    36 TDLDIFEINEVAGLDLVEGDILIEEGESRNTILGEQYRWP-TTVPYFLD-NSLEINAKGVILKAF 98

  Fly   132 KEYHDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVG-RRSGGQVLNLNTPKCVTHGVVVHELLHA 195
            ::|..:|||.|:|:.....:..:.||  |||:|.|| |:.|.|.|::.: .|.:.|.|.||.|||
Zfish    99 EQYRLKTCIDFKPWNGESNYIFVFKG--SGCYSKVGNRQMGKQELSIGS-NCDSLGTVEHEFLHA 160

  Fly   196 LGFYHQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKA 260
            ||.:|:||.::||:||.|.|:.|.||..||||.|..|..::.||.|||.||||||..:|:|..:.
Zfish   161 LGLWHEQSRSDRDDYVIIVWDQIQDGKEHNFNLYDETQSSSLGVPYDYSSVMHYSKTSFNKGSEP 225

  Fly   261 TIEPLDP--YASLGQRRGLSDKDVSKLNEMYEQDCSEDYL 298
            ||....|  ...:|||...||.|:.|||.:|....|..:|
Zfish   226 TIVTKIPEFLNVIGQRMEFSDNDLLKLNRLYNCTTSSTFL 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	84/193 (44%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	81/181 (45%)
mep1ba	NP_001070089.2	ZnMc_meprin	29..258	CDD:239809	96/226 (42%)
		Astacin	72..260	CDD:279708	84/192 (44%)
		MAM	268..432	CDD:279023
		MAM	268..430	CDD:99706
		MATH_Meprin_Beta	430..599	CDD:239751
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	153	1.000	Domainoid score	I4243
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25214
orthoMCL	1	0.900	-	-		OOG6_108702
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2664
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.840