DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fu and stk36

DIOPT Version :9

Sequence 1:	NP_477499.1	Gene:	fu / 32855	FlyBaseID:	FBgn0001079	Length:	805	Species:	Drosophila melanogaster
Sequence 2:	NP_001135663.1	Gene:	stk36 / 100216223	XenbaseID:	XB-GENE-5998666	Length:	363	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	130/248 - (52%)
Similarity:	179/248 - (72%)	Gaps:	3/248 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VVAIKVISKRGRATKELKNLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFALMDLHRYLSY 93
            |||:|.|.|.||:.||||.|:||..|...|:||:::.|::|.|::.::.||||:|..:|.:.|..
Frog     2 VVALKFIPKVGRSEKELKGLKREIQIMRDLRHPNIVRMLDSCETEREVVVVTEYAEGELFKILED 66

  Fly    94 NGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLT 158
            :|...||..|.::..||||||||||:||||||:||||:||.|:...||||||.||.::|.|.::.
Frog    67 DGHFPEELVRDISAQLVSALYYLHSHRILHRDMKPQNILLSKDGTVKLCDFGFARELSLDTLMVR 131

  Fly   159 SIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTL 223
            |||||||||:|||:.|:||||.:|:|:||||.||.:.|.|||.|.||..||.:|..:.|:||..:
Frog   132 SIKGTPLYMSPELILERPYDHRSDLWALGCIVYELLVGTPPFYAHSIFQLVSIITQQAVRWPRGV 196

  Fly   224 TSECRSFLQGLLEKDPGLRISWTQLLCHPFVEGRIFIAETQAEAAKESPFTNP 276
            :.|..:||||||.|||.:|:||.:||.|||::.::.:.|   |.|..||||:|
Frog   197 SPELTNFLQGLLTKDPAVRLSWPELLRHPFIKDQVVVVE---ENANNSPFTSP 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fu	NP_477499.1	STKc_STK36	2..254	CDD:270904	121/224 (54%)
fu	NP_477499.1	Pkinase	4..254	CDD:278497	121/224 (54%)
stk36	NP_001135663.1	PKc_like	2..227	CDD:304357	121/224 (54%)
stk36	NP_001135663.1	S_TKc	2..227	CDD:214567	121/224 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	284	1.000	Domainoid score	I1609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H80351
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005852
OrthoInspector	1	1.000	-	-		oto104720
Panther	1	1.100	-	-	LDO	PTHR22983
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6666
SonicParanoid	1	1.000	-	-		X5605
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.130