Protein Alignment CG6659 and DPY19L4

DIOPT Version :9

• Sequence 1: NP_573317.1
• Gene: CG6659 / 32854
• FlyBaseID: FBgn0030946
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: XP_005250951.2
• Gene: DPY19L4 / 286148
• HGNCID: 27829
• Length: 797
• Species: Homo sapiens
• Alignment Length: 913
• Identity: 186/913 - (20%)
• Similarity: 323/913 - (35%)
• Gaps: 297/913 - (32%)

  Fly     2 REPN--LYVILSHALIGC------GFFFLYVQHVRVIFETRTNIQQLNQLEREALLRREDALYYA 58
            |.|.  |:...:...|||      |  .:|..::....|.:.......:||||...:.:.|:||:
Human   113 RAPKHVLFQRFAKIFIGCLAAVTSG--MMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYS 175

  Fly    59 FYKQLAEGPDFWHGYEQLKNVTDIEYPHSVNVLQRFYVLPELVTAYFFHVVRSGFNPMVQPMQFY 123
            :||.:.:.|.|..|..:|.:........::|.:|:..:.|||:.:..:..  :|.|.:::|:.||
Human   176 YYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQQMSLYPELIASILYQA--TGSNEIIEPVYFY 238

  Fly   124 LEFVWLMGGVTLLVLYLYGTLLSENIFGGIYGVISYLMFHSFVAKI-YERPLARENFAFPFIFLQ 187
            :..|:.:.|:.:..|::...|:|.....|:..|..:::......:| |..|| |||:|.|:...|
Human   239 IGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPL-RENWALPYFACQ 302

  Fly   188 MFYLCICIGRIIHRQRHTSRMFMIFAMSLFTACALLSWQFSTFIFTTQILIMMTSWNASALPTAL 252
            :..|   .|.:..........|....||..|...::.|::|.::...|           |:...|
Human   303 IAAL---TGYLKSNLNTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQ-----------AISLFL 353

  Fly   253 VNAFVLD-----------YSLSHLLGHALAFVMSHGNSQLLLTWQLSISLFLFLITMVRQLRHVR 306
            ::.|.::           |..|..||:.|.|    .|..||::..||:...|.|
Human   354 LDTFSVEQSDKVYEVYKIYIFSLFLGYLLQF----ENPALLVSPLLSLVAALML----------- 403

  Fly   307 SRRLGHAQDLLNGDLFSLKFLMLTLLLASSVQTTLIELFNRAGVVSVTEGDQQHFFDICAHWALQ 371
                             .|.|.|.:...|.| ..:|::.|              |:.:|. ..:.
Human   404 -----------------AKCLQLNVKKGSFV-AKIIKVIN--------------FYLVCT-LTIT 435

  Fly   372 VNV---GFVAHLSACNPQYARVAWSELWQLVKTMIVKPYCMYGVVMLAMFFRRWRKSGAPVSALT 433
            :|:   .||.|             .|...::|.:.||    :|:.|...|...|        .|.
Human   436 LNIIMKMFVPH-------------KENGHMLKFLEVK----FGLNMTKNFTMNW--------LLC 475

  Fly   434 EEQRERARKYVLEDFIEEHFVSMSDMSSKETEKQLYKCFRL-LKSCDYDYERYKRAQASLRKEQP 497
            :|..:...    :||    |:.:       |:..|...:.| |..|
Human   476 QESLQAPS----QDF----FLRL-------TQSSLLPFYILVLIIC------------------- 506

  Fly   498 PARDDFMQDIKRLRAQINRNSVKQRKERAQETKEAATDGASTPTEEEDKDPEAESESKKKNQEPG 562
                 |:..::.:..:||..|:|:                 |.|.|:.:
Human   507 -----FLSMLQVIFRRINGKSLKE-----------------TVTLEDGR---------------- 533

  Fly   563 SGETETESAADPTETPPSRSADNEEEEEEHSATAAGCGSNSSGHRQRKRSSSRRSSVVPTANAQI 627
                                                     .|.|.
Human   534 -----------------------------------------IGERP------------------- 538

  Fly   628 LNMHYVYSFLQMLVFTLIGLAVRKLFFLSFTQGCVIAP-TVCS-KLW-----YHRQRNIFWSVSL 685
               ..:|..:..::...:.:.:..|.::.....|::|. .||| :||     :.|.|.:. .:.|
Human   539 ---EIIYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVH-PILL 599

  Fly   686 AVFLLSMFDPGMVNIR--EEYFPTRYSKSGD-------DLDSMLEWIKLNTERDAVFAGPVDIIG 741
            |: :|||..|.::.:.  :|:||...::..:       |...::.|||......|||||...::|
Human   600 AL-ILSMAVPTIIGLSLWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMG 663

  Fly   742 TVHL-----TTKRPIVNHAHLEMRQIAERTEHVYSVYSRQQSSDIYNQCAQLKIQYLIISLDECT 801
            .:.|     .|..|:.|...|     .:|.|::|.:||::.:.|||......|..|||:. |...
Human   664 AIKLCTGWMVTSLPLYNDDDL-----LKRNENIYQIYSKRSAEDIYKILTSYKANYLIVE-DAIC 722

  Fly   802 NEV--RDDC---DLLAIWD--------DKQPAYQKYPQFCHELLHKNVP---SFLKVFANDHYGI 850
            |||  ...|   |||.|.:        ||. .|.||.:||||:.....|   .|.:|:.|..|.:
Human   723 NEVGPMRGCRVKDLLDIANGHMVCEEGDKL-TYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFV 786

  Fly   851 IKM 853
            .|:
Human   787 YKI 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6659	NP_573317.1	Dpy19	18..852	CDD:287052	179/886 (20%)
		Neuromodulin	521..>599	CDD:284117	3/77 (4%)
DPY19L4	XP_005250951.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1115173at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42002
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.710