DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ing3 and YNG1

DIOPT Version :9

Sequence 1:	NP_573316.1	Gene:	Ing3 / 32853	FlyBaseID:	FBgn0030945	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_014707.1	Gene:	YNG1 / 854230	SGDID:	S000005590	Length:	219	Species:	Saccharomyces cerevisiae

Alignment Length:	202	Identity:	67/202 - (33%)
Similarity:	86/202 - (42%)	Gaps:	71/202 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   496 HQEKKQKKKLTTALTLPTVQPTAGSSSGNSIGSSSSISLESV-NKLTTSAALAAASATTTYMSVG 559
            |..|:.||:|       .:|        .|:..:.:.|||:: :|||
Yeast    73 HFLKQHKKEL-------EIQ--------KSVTKNFNSSLENIKSKLT------------------ 104

  Fly   560 GQALLAMTPGGGGGGNLAESSAEGVPAGMIAMNLPTT-------TVTPGSSLTIGEN-GLVVEQT 616
                            |.|..|...|..::.:||...       ::|   |.|||.| |.|.|..
Yeast   105 ----------------LEEPGAYKEPKLLLKINLKKAKSRERKESIT---SPTIGINQGDVTEGN 150

  Fly   617 NEGEWSYDPNEPRYCTCNQVSYGDMVACDNDACPYEWFHYPCVGITQPPKGKWYCPK-C--TASM 678
            |.       .|..||.|..||||.||||||.|||:|||||.|||:.|.|||||||.| |  .|:.
Yeast   151 NN-------QEEVYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYCSKDCKEIANQ 208

  Fly   679 RRRGNRK 685
            |.:..|:
Yeast   209 RSKSKRQ 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ing3	NP_573316.1	ING	3..103	CDD:289749
Ing3	NP_573316.1	PHD_ING3	630..674	CDD:277060	33/44 (75%)
YNG1	NP_014707.1	TNG2	1..206	CDD:227367	64/191 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	1	1.000	-	-		otm46939
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10333
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
TreeFam	0	0.000	Not matched by this tool.
	7	6.940