Protein Alignment Ing3 and ing5a

DIOPT Version :10

• Sequence 1: NP_573316.1
• Gene: Ing3 / 32853
• FlyBaseID: FBgn0030945
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001093519.1
• Gene: ing5a / 792168
• ZFINID: ZDB-GENE-031016-1
• Length: 242
• Species: Danio rerio
• Alignment Length: 680
• Identity: 97/680 - (14%)
• Similarity: 150/680 - (22%)
• Gaps: 442/680 - (65%)

  Fly     2 LYLEDYLEMIEHLPQELRDRFTEMRELDLAVQNNMDSLDKKAHMFFKQCKRDELQHESMDTEFHS 66
            :|||.||:.||:||.||:..||.|||||...:.....:||.|..:....:  .|..:........
Zfish     5 IYLEHYLDSIENLPCELQRNFTLMRELDNRAEEKKCEIDKLAEEYIANVR--NLAPDQRVEHLQK 67

  Fly    67 LRGEYFKVMEDADEKVAIATQIHELVERYLRRLDSELFKFKCELEADNNGITEILERRSLELDGN 131
            ::..:.|..|.:|:||.:|.|.:|:|::::||||::|.:|:.||
Zfish    68 IQNGFSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFENEL--------------------- 111

  Fly   132 STAATALLLSMNQKENRYYGASSANTMVNSSTGHATGAATGSSGIALVSGAAGTGGALSSISTAQ 196
                                                                             
Zfish   112 ----------------------------------------------------------------- 111

  Fly   197 LGSSQRHRKLEKRRETICTVPVQEKRANLNHSLPVVGSGSTTAAAASSSSATTAAAAASLASATT 261
                                  :||
Zfish   112 ----------------------KEK---------------------------------------- 114

  Fly   262 AQTHVSNHIGSIAATHLTLPVAMGVAGGSSSLASSSLATGTGSLVRQLPTNLTHTVLSTSGGATA 326
                                  :.|:|..|                  |.|.||..::
Zfish   115 ----------------------LDVSGYES------------------PDNRTHKKVT------- 132

  Fly   327 AAAAGGNSTSVVAAGTAHGHAHVSGHSAAGATVTYNLQQLGGGAAASSAIAAAASQAIVATQQMQ 391
                                                                             
Zfish   133 ----------------------------------------------------------------- 132

  Fly   392 QGRRTASLKASYEAIHGTAGTTTDFWTQAGQGGLQQSTAGSVTVAAGTALATGAAGGSSTGSHHS 456
                                         |:|.|::.....
Zfish   133 -----------------------------GRGNLKEKRRPK------------------------ 144

  Fly   457 HHSQSHHGGHGHGHGHGHGHGHGHGHHSSSGHGGGHSSHHQEKKQKKKLTTALTLPTVQPTAGSS 521
                                            |.|..|...|..:|||:..:...|
Zfish   145 --------------------------------GRGRKSSDDESPRKKKMKNSPEFP--------- 168

  Fly   522 SGNSIGSSSSISLESVNKLTTSAALAAASATTTYMSVGGQALLAMTPGGGGGGNLAESSAEGVPA 586
                                                   :::|.:.|..
Zfish   169 ---------------------------------------ESILPVHPSD---------------- 178

  Fly   587 GMIAMNLPTTTVTPGSSLTIGENGLVVEQTNEGEWSYDPNEPRYCTCNQVSYGDMVACDNDACPY 651
               .:::|.                            |||||.||.|:|||||:|:.|||..||.
Zfish   179 ---VLDMPV----------------------------DPNEPTYCLCHQVSYGEMIGCDNPDCPI 212

  Fly   652 EWFHYPCVGITQPPKGKWYCPKCTASMRRR 681
            ||||:.||.:|..|||||:||:||...:::
Zfish   213 EWFHFACVDLTTKPKGKWFCPRCTQDRKKK 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ing3	NP_573316.1	ING	3..103	CDD:463768	35/99 (35%)
		PHD_ING3	630..674	CDD:277060	28/43 (65%)
ing5a	NP_001093519.1	TNG2	1..235	CDD:227367	95/671 (14%)
		ING_ING5	12..104	CDD:341096	30/93 (32%)