Protein Alignment Ing3 and Ing3

DIOPT Version :10

• Sequence 1: NP_573316.1
• Gene: Ing3 / 32853
• FlyBaseID: FBgn0030945
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_076115.3
• Gene: Ing3 / 71777
• MGIID: 1919027
• Length: 421
• Species: Mus musculus
• Alignment Length: 685
• Identity: 215/685 - (31%)
• Similarity: 285/685 - (41%)
• Gaps: 267/685 - (38%)

  Fly     1 MLYLEDYLEMIEHLPQELRDRFTEMRELDLAVQNNMDSLDKKAHMFFKQCKRDELQHESMDTEFH 65
            ||||||||||||.||.:||||||||||:||.|||.||.|:::...||...|::  :.|..:.:..
Mouse     1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKN--KPEWREEQMA 63

  Fly    66 SLRGEYFKVMEDADEKVAIATQIHELVERYLRRLDSELFKFKCELEADNNGITEILERRSLELDG 130
            |::.:|:|.:|||||||.:|.||::||:|:||:||.||.|||.||||||.||||||||||||||.
Mouse    64 SIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDA 128

  Fly   131 NSTAATALLLSMNQKENRYYGASSANTMVNSSTGHATGAATGSSGIALVSGAAGTGGALSSISTA 195
            .|..                        ||:...|:
Mouse   129 PSQP------------------------VNNHHAHS----------------------------- 140

  Fly   196 QLGSSQRHRKLEKRRETICTVPVQEKRANLNHSLPVVGSGSTTAAAASSSSATTAAAAASLASAT 260
                   |..:|||:                       ...|:..||:.........:.:|.|..
Mouse   141 -------HTPVEKRK-----------------------YNPTSHHAAADHIPEKKFKSEALLSTL 175

  Fly   261 TAQTHVSNHIGSIAATHLTLPVAMGVAGGSSSLASSSLATGTGSLVRQLPTNLTHTVLSTSGGAT 325
            |:.....|.:|               ...::|.||.:.|...
Mouse   176 TSDASKENTLG---------------CRNNNSTASCNNAYNV----------------------- 202

  Fly   326 AAAAAGGNSTSVVAAGTAHGHAHVSGHSAAGATVTYNLQQLGGGAAASSAIAAAASQAIVATQQM 390
                   ||:..:|                    :||:..|..||.| .||..||:||:.||.||
Mouse   203 -------NSSQPLA--------------------SYNIGSLSSGAGA-GAITMAAAQAVQATAQM 239

  Fly   391 QQGRRTASLKASYEAIHGTAGTTTDFWTQAG-QGGLQQSTAGSVTVAAGTALATGAAGGSSTGSH 454
            ::||||:||||||||.     ...||  |.| :..:.:.|||..:.:|.....|..|..|:|.|.
Mouse   240 KEGRRTSSLKASYEAF-----KNNDF--QLGKEFSIPRETAGYSSSSALMTTLTQNASSSATDSR 297

  Fly   455 HSHHSQSHHGGHGHGHGHGHGHGHGHGHHSSSGHGGGHSSHHQEKKQKKKLTTALTLPTVQPTAG 519
                                               .|..|.:..|...::
Mouse   298 -----------------------------------SGRKSKNNTKSSSQQ--------------- 312

  Fly   520 SSSGNSIGSSSSISLESVNKLTTSAALAAASATTTYMSVGGQALLAMTPGGGGGGNLAESSAEGV 584
            |||.:|..||||:||             .:|::|....|..||
Mouse   313 SSSSSSSSSSSSLSL-------------CSSSSTVVQEVSQQA---------------------- 342

  Fly   585 PAGMIAMNLPTTTVTPGSSLTIGENGLVVEQTNEGEWSYDPNEPRYCTCNQVSYGDMVACDNDAC 649
                        ||.|.|           :..::.:|:|||||||||.|||||||:||.|||..|
Mouse   343 ------------TVVPES-----------DSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDC 384

  Fly   650 PYEWFHYPCVGITQPPKGKWYCPKCTASMRRRGNR 684
            |.|||||.|||:|:.|||||:||:|||:|:|||:|
Mouse   385 PIEWFHYGCVGLTEAPKGKWFCPQCTAAMKRRGSR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ing3	NP_573316.1	ING	3..103	CDD:463768	54/99 (55%)
		PHD_ING3	630..674	CDD:277060	32/43 (74%)
Ing3	NP_076115.3	ING	3..102	CDD:463768	54/98 (55%)
		TNG2	4..413	CDD:227367	129/408 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..163		4/33 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..323		4/36 (11%)
		PHD_ING3	365..409	CDD:277060	26/43 (60%)