DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ing3 and ing1

DIOPT Version :9

Sequence 1:	NP_573316.1	Gene:	Ing3 / 32853	FlyBaseID:	FBgn0030945	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_001035446.1	Gene:	ing1 / 678608	ZFINID:	ZDB-GENE-060421-4388	Length:	309	Species:	Danio rerio

Alignment Length:	179	Identity:	63/179 - (35%)
Similarity:	81/179 - (45%)	Gaps:	25/179 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   522 SGNSIGSSSSISLESVNKLTTSAALAAASATT-------TYMSV---GGQALLAMTPGGGG--GG 574
            |..|:||:.| ::.:....|.|..|.:||..|       |..||   ||:.......|...  ..
Zfish   124 SSVSVGSTPS-AITTTAMTTISDILLSASKLTANRRREETPSSVDKSGGKRSRRQKNGSENRENS 187

  Fly   575 NLAESSAEGVPAGMIAMNLPTTTVTPGSSLTIGENGLVVEQTNE---GEWSYDPNEPRYCTCNQV 636
            |.:....|.|.:|......|..:.|........::    :|..|   .:...|||||.||.|.||
Zfish   188 NYSLEHIEDVSSGTPKEKKPKASATSSKKKKRSKS----KQDREPSPTDLPIDPNEPTYCLCEQV 248

  Fly   637 SYGDMVACDNDACPYEWFHYPCVGITQPPKGKWYCPKCTASMRRRGNRK 685
            |||:|:.||||.|..||||:.||.:...||||||||||     |..|.|
Zfish   249 SYGEMIGCDNDECTIEWFHFSCVDLHHKPKGKWYCPKC-----RGDNEK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ing3	NP_573316.1	ING	3..103	CDD:289749
Ing3	NP_573316.1	PHD_ING3	630..674	CDD:277060	28/43 (65%)
ing1	NP_001035446.1	ING	17..111	CDD:289749
		TNG2	18..287	CDD:227367	60/172 (35%)
		PHD_ING1_2	242..286	CDD:277059	28/43 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850