Protein Alignment Ing3 and Ing5

DIOPT Version :10

• Sequence 1: NP_573316.1
• Gene: Ing3 / 32853
• FlyBaseID: FBgn0030945
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_079730.1
• Gene: Ing5 / 66262
• MGIID: 1922816
• Length: 240
• Species: Mus musculus
• Alignment Length: 691
• Identity: 106/691 - (15%)
• Similarity: 151/691 - (21%)
• Gaps: 467/691 - (67%)

  Fly     2 LYLEDYLEMIEHLPQELRDRFTEMRELDLAVQNNMDSLDKKAHMFFKQCKRDELQHESMDT---- 62
            :|||.||:.||:||.||:..|..|||||...:      ||||.:       |.|..|.:.|
Mouse     5 MYLEHYLDSIENLPCELQRNFQLMRELDQRTE------DKKAEI-------DILAAEYISTVKTL 56

  Fly    63 -------EFHSLRGEYFKVMEDADEKVAIATQIHELVERYLRRLDSELFKFKCELEADNNGITEI 120
                   ....::..|.|..|.:|:||.:|.|.:|:|::::||||::|.:|:.:|:...:|
Mouse    57 SSAQRVEHLQKIQSAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDRMDG---- 117

  Fly   121 LERRSLELDGNSTAATALLLSMNQKENRYYGASSANTMVNSSTGHATGAATGSSGIALVSGAAGT 185
                   .|..||.|.:|....:|||.|            ||.|
Mouse   118 -------SDFESTGARSLKKGRSQKEKR------------SSRG--------------------- 142

  Fly   186 GGALSSISTAQLGSSQRHRKLEKRRETICTVPVQEKRANLNHSLPVVGSGSTTAAAASSSSATTA 250
                                                                             
Mouse   143 ----------------------------------------------------------------- 142

  Fly   251 AAAASLASATTAQTHVSNHIGSIAATHLTLPVAMGVAGGSSSLASSSLATGTGSLVRQLPTNLTH 315
                                                                             
Mouse   143 ----------------------------------------------------------------- 142

  Fly   316 TVLSTSGGATAAAAAGGNSTSVVAAGTAHGHAHVSGHSAAGATVTYNLQQLGGGAAASSAIAAAA 380
                                                                             
Mouse   143 ----------------------------------------------------------------- 142

  Fly   381 SQAIVATQQMQQGRRTASLKASYEAIHGTAGTTTDFWTQAGQGGLQQSTAGSVTVAAGTALATGA 445
                       :||||
Mouse   143 -----------RGRRT------------------------------------------------- 147

  Fly   446 AGGSSTGSHHSHHSQSHHGGHGHGHGHGHGHGHGHGHHSSSGHGGGHSSHHQEKKQKKKLTTALT 510
                                                           |.....||:|.|
Mouse   148 -----------------------------------------------SEEDTPKKKKHK------ 159

  Fly   511 LPTVQPTAGSSSGNSIGSSSSISLESVNKLTTSAALAAASATTTYMSVGGQALLAMTPGGGGGGN 575
                   :||...:||                                     |::.|..
Mouse   160 -------SGSEFTDSI-------------------------------------LSVHPSD----- 175

  Fly   576 LAESSAEGVPAGMIAMNLPTTTVTPGSSLTIGENGLVVEQTNEGEWSYDPNEPRYCTCNQVSYGD 640
                          .:::|.                            |||||.||.|:|||||:
Mouse   176 --------------VLDMPV----------------------------DPNEPTYCLCHQVSYGE 198

  Fly   641 MVACDNDACPYEWFHYPCVGITQPPKGKWYCPKCTASMRRR 681
            |:.|||..||.||||:.||.:|..|||||:||:|....|::
Mouse   199 MIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ing3	NP_573316.1	ING	3..103	CDD:463768	39/110 (35%)
		PHD_ING3	630..674	CDD:277060	28/43 (65%)
Ing5	NP_079730.1	ING_ING5	12..104	CDD:341096	34/104 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	115..165		24/408 (6%)
		PHD_ING5	187..235	CDD:277155	29/47 (62%)