Protein Alignment Ing3 and ing3

DIOPT Version :9

• Sequence 1: NP_573316.1
• Gene: Ing3 / 32853
• FlyBaseID: FBgn0030945
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_957231.1
• Gene: ing3 / 393911
• ZFINID: ZDB-GENE-040109-3
• Length: 416
• Species: Danio rerio
• Alignment Length: 687
• Identity: 212/687 - (30%)
• Similarity: 287/687 - (41%)
• Gaps: 276/687 - (40%)

  Fly     1 MLYLEDYLEMIEHLPQELRDRFTEMRELDLAVQNNMDSLDKKAHMFFKQCKRD--ELQHESMDTE 63
            ||||||||||||.||.:||||||||||:||.|||.||.|:::.:.||...|::  |.:.|.|:.
Zfish     1 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVNEFFTNAKKNKPEWREEQMEI- 64

  Fly    64 FHSLRGEYFKVMEDADEKVAIATQIHELVERYLRRLDSELFKFKCELEADNNGITEILERRSLEL 128
               ::.:|:|.:|||||||.:|.||::||:|:||:||.||.|||.||||||.||||||||||||:
Zfish    65 ---IKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLEM 126

  Fly   129 DGNSTAATALLLSMNQKENRYYGASSANTMVNSSTGHATGAATGSSGIALVSGAAGTGGALSSIS 193
            |                        |.:..||:...|:
Zfish   127 D------------------------SPSQPVNNHHVHS--------------------------- 140

  Fly   194 TAQLGSSQRHRKLEKRRETICTVPVQEKRANLNHSLPVVGSGSTTAAAASSSSATTAAAAASLAS 258
                     |..:|||:                :|.|.
Zfish   141 ---------HTTVEKRK----------------YSTPA--------------------------- 153

  Fly   259 ATTAQTHVSNHIGSIAATHLTLPVAMGVAGGSSSLASSSLATGTGSLVRQLPTNLTHTVLSTSGG 323
                 .|.:.|:                  ......|.:|          |.|..:......:.|
Zfish   154 -----HHTTEHV------------------PEKKFKSEAL----------LSTLTSDATKENTPG 185

  Fly   324 ATAAAAAGGNSTSVVAAGTAHGHAHVSGHSAAGATVTYNLQQL-GGGAAASSAIAAAASQAIVAT 387
            ..|.:.:..||...|             :|:...|.:|||..| .|.||.:.||:.||:||:.||
Zfish   186 CRANSTSSSNSMYNV-------------NSSQSLTSSYNLSPLPAGPAAGAGAISMAAAQAVQAT 237

  Fly   388 QQMQQGRRTASLKASYEAIHGTAGTTTDFWTQAGQGGLQQSTAGSVTVAAGTALATGAAGGSSTG 452
            .||::||||:||||||||:........||...      :.|::.|.:..|.| |.......:|:.
Zfish   238 AQMKEGRRTSSLKASYEAVKNNDFLGRDFTMS------RDSSSYSSSALAST-LTQPLTSTNSSD 295

  Fly   453 SHHSHHSQSHHGGHGHGHGHGHGHGHGHGHHSSSGHGGGHSSHHQEKKQKKKLTTALTLPTVQPT 517
            |..:..::|:                            ..||:||                   :
Zfish   296 SRTARKTKSN----------------------------TKSSNHQ-------------------S 313

  Fly   518 AGSSSGNSIGSSSSISLESVNKLTTSAALAAASATTTYMSVGGQALLAMTPGGGGGGNLAESSAE 582
            :.|||.:|:.|.||                                               |||
Zfish   314 SSSSSSSSLSSCSS-----------------------------------------------SSA- 330

  Fly   583 GVPAGMIAMNLPTTTVTPGSSLTIGENGLVVEQTNEGEWSYDPNEPRYCTCNQVSYGDMVACDND 647
                  :|..|..||||.            .:.:::.:|:|||||||||.|||||||:||.|||.
Zfish   331 ------LAHELVQTTVTE------------TDTSSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQ 377

  Fly   648 ACPYEWFHYPCVGITQPPKGKWYCPKCTASMRRRGNR 684
            .||.|||||.|||:|:.||||||||:|||:|:|||:|
Zfish   378 DCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSR 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ing3	NP_573316.1	ING	3..103	CDD:289749	55/101 (54%)
		PHD_ING3	630..674	CDD:277060	33/43 (77%)
ing3	NP_957231.1	ING	3..102	CDD:289749	56/102 (55%)
		TNG2	4..408	CDD:227367	204/676 (30%)
		PHD_ING3	360..404	CDD:277060	33/43 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590297
Domainoid	1	1.000	116	1.000	Domainoid score	I5930
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	1	1.000	-	-		oto38765
orthoMCL	1	0.900	-	-		OOG6_107420
Panther	1	1.100	-	-	LDO	PTHR10333
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.830