Protein Alignment Nup35 and Nup35

DIOPT Version :10

• Sequence 1: NP_573314.1
• Gene: Nup35 / 32851
• FlyBaseID: FBgn0030943
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_081367.1
• Gene: Nup35 / 69482
• MGIID: 1916732
• Length: 325
• Species: Mus musculus
• Alignment Length: 355
• Identity: 99/355 - (27%)
• Similarity: 156/355 - (43%)
• Gaps: 70/355 - (19%)

  Fly     2 EPMNLGSPVNSPGSNQTQYLPPFLLGD-PQGITPHKNTLS-PKTGRSNISFATSPGGSSPHELNR 64
            |||.||||.:.......|:||.||:|| |..:||...::| |..|...:......|||.|..:
Mouse    16 EPMMLGSPTSPKTGANAQFLPGFLMGDLPAPVTPQPRSISGPSVGVMEMRSPLLAGGSPPQPV-- 78

  Fly    65 SALSTRTLFAAQGGAHTAVGANSSTTAHGQTHSHHQTGPPTQGLFD-----SLREQSVTPKKKNH 124
                              |.|          |......||.:.::|     .|....:|.:::.:
Mouse    79 ------------------VPA----------HKDKSGAPPVRSIYDDISSPGLGSTPLTSRRQAN 115

  Fly   125 LGMLQLQSPNQSYQSSYHTNDSFAP---GAPNAINASMRALCSPLGATASPAGGLGTSVTTGGNS 186
            :.:  ||||.....:.......|:|   |.|.      :...||  |...|....|.|:|:  ..
Mouse   116 ISL--LQSPLVGATTPVPGQSMFSPANIGQPR------KTTLSP--AQLDPFYTQGDSLTS--ED 168

  Fly   187 RLSDFWVTIFGFPPGAGSMVLQHFTVCGTIVDVVHAPQN-GNWMYVRYSSRIESDKALNYNEKII 250
            .|.|.|||:||||..:.|.:|..|...|.|:.  |...| ||||::||.|::::.|||:.:.:|.
Mouse   169 HLDDTWVTVFGFPQASASYILLQFAQYGNILK--HVMSNTGNWMHIRYQSKLQARKALSKDGRIF 231

  Fly   251 AGNVMVGVSRCTDRSVIDKENIG---------SVPNAEIGDPPTS-----PSAIRPFSQQSYKLA 301
            ..::|:||..|.|::|::..:.|         :.|...:|.|..|     .|.:||.: .:||.:
Mouse   232 GESIMIGVKPCIDKNVMENSDRGVLSSPSLAFTTPIRTLGTPTQSGSTPRVSTMRPLA-TAYKAS 295

  Fly   302 RKDNIISPQKDVPQKSSGLMDKAMDLIFGW 331
            ..|..:...:..|:|...|:.:||:.:|||
Mouse   296 TSDYQVISDRQTPKKDESLVSRAMEYMFGW 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup35	NP_573314.1	Nup35_RRM	190..268	CDD:398713	32/78 (41%)
Nup35	NP_081367.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..92		4/26 (15%)
		RRM_Nup53	171..244	CDD:410121	26/73 (36%)