Protein Alignment Rip11 and rab11fip1

DIOPT Version :9

• Sequence 1: NP_573313.2
• Gene: Rip11 / 32850
• FlyBaseID: FBgn0027335
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: XP_012814911.2
• Gene: rab11fip1 / 734108
• XenbaseID: XB-GENE-982593
• Length: 1056
• Species: Xenopus tropicalis
• Alignment Length: 1131
• Identity: 245/1131 - (21%)
• Similarity: 404/1131 - (35%)
• Gaps: 398/1131 - (35%)

  Fly     2 WSPTHCSVTVQRARGLLTKGKNGTNNCFVTIALGKEKYQTSVKDKAETSVNWNEECELKIP---- 62
            |.|||..|||.:|:||..|||.|:|:.:..|.||||||.|:|.:|::..| |.||...::|
 Frog    10 WFPTHVQVTVLQAKGLKPKGKAGSNDAYAIIQLGKEKYSTTVAEKSQAPV-WKEEATFEVPLLHN 73

  Fly    63 DQGNRAELTLTCLHRNNLGIDEFLGQATLPLNEM-DVYDRPRAKWFKLESKPGKEKKNKERGELE 126
            |...|..:.:..:||..:|:|:||||..|.|.|: ...:|.:.:|:.|.||||  ||.||||::|
 Frog    74 DNQERCTVRVIVMHRALVGMDKFLGQLELNLWELHQSRNRRKVQWYPLRSKPG--KKEKERGQIE 136

  Fly   127 VRIAFVVK--SGSLTDLSKKDKHKSSIGQLASSVGGSLLSIGNGEKRRGIKKLAGSLSSKLH--- 186
            |.:.|:..  :.|:.|||.|:|.:|::|:|...:        .|:|..|....|.::...::
 Frog   137 VEVQFMRNNMTASMFDLSMKEKSRSTLGKLRDKI--------KGKKHEGFPDTASAIVPSMNQYD 193

  Fly   187 ----------IRSKKKN-------QEAGADDSSSFGGSFASLGTPN--------SSNGRGQNGGS 226
                      .:||.||       ::.....|.|...:|....:|.        ||:.....|..
 Frog   194 SDEDMPAAEKKKSKLKNLFSKPGLKKNSISQSMSVLPTFPPSSSPKTVLRPAEFSSDFTPPTGSP 258

  Fly   227 GRRR---------GGQRAGEADPGVISEDEDE--FVFDNLSHKS-----SGSSLNIQRIGLQ--- 272
            ...|         ..:|...||...:|.::.|  .:|..:..|:     |...:|...:.::
 Frog   259 ASERRFPHLPVIMTHKRTVSADTSQLSSNKKEGLSLFSGMKPKNDPITRSNLCINGNHVYMEESE 323

  Fly   273 --------PPPVGTPNFTPRHPSPLLNNGVSGVGSGSAK-GKQAVLPATLDEDASIDAEMEQLEL 328
                    .....:|....::|   |......:.|.:.| .|.::.|   :::.:..|..:.|:
 Frog   324 TRSESPKDSSQTNSPQIVRKNP---LYASAENLSSKTPKEAKNSLFP---EKEQTPAASNDSLK- 381

  Fly   329 DFSVRAHARANANASASGNASTLPPPSKPPRIPLSQVDEQP----------------AAGSLERE 377
                      ::..|||.|:.:..|.||.|.:| |.|.::.                ..|..:..
 Frog   382 ----------SSTVSASQNSKSEEPISKTPPLP-SDVPKEAKDNKKQENKKSSLLSLVTGKKDTP 435

  Fly   378 KPKEKPAEVESDKDEWASKLYGGGKYLEIGSSNSLKRRS---WEDRV-------PLPAS------ 426
            |..|..:.|...|.: .||..|..|.:|..|.|..|:.|   :||.:       |||.|
 Frog   436 KVPENESSVAPLKGD-MSKATGDNKKIEQSSINVTKKTSLNPFEDDMEEEKKPEPLPTSAKTSAV 499

  Fly   427 ---------VEEPPPLHSSSSSSSSSSDSDDDDEKPPQAAPPPVPVPASLP-VPSAAASTASADP 481
                     .|....|.|||.|:|::|.|...|           .||.||| .|:  ||.|.:.|
 Frog   500 KPRLDVSSEAETKAKLSSSSLSNSAASISGGQD-----------GVPTSLPDFPT--ASNAPSSP 551

  Fly   482 V-----VATSSSLFSPDVEHRNFDT---------------------------FNASFAKYEQR-- 512
            :     :...:.:.:|...:.:::|                           ||   .|.::|
 Frog   552 LEHYLSLQCDNKVETPVESYTDYETPSVPLFWRSGLSQSKQPEPREVHVVEPFN---EKTKERKT 613

  Fly   513 ---------------NSTA--------------------IFADEPELEDLTVELEK--------- 533
                           ||.|                    .|.|.|..:..::|.||
 Frog   614 YVKSLLDQLTRKSPTNSVADADTVDVDLVKGVFPIQDSSPFDDIPHTDTDSLESEKSDVQLTKTL 678

  Fly   534 ---PAPTPTAR----------------PKPQPRA------TADLRAEEEKAKEEAARQLRAEEDA 573
               |.|.|..:                |||.||:      .||..|.......|.|....:.::.
 Frog   679 KETPKPAPRTQSAPKKQEPKDEIKPVPPKPAPRSATKVNKAADDSAPASSTPPEKALDTYSNQEL 743

  Fly   574 RLEAEL------------------RLNEERLREEEEAMQRELEEEKERQKQLQMDE--------Q 612
            :..:.:                  :::|..||.:|..:..|..|.....:||:..:        .
 Frog   744 QQASNVGSSLNSGQAITEVKMATPKISEYSLRLDELPVIPENPEGTSDDEQLETKDDIFSSHSSN 808

  Fly   613 QRREAKRWEEDQRLLSFAKRSTSLEEPVPEKQELKHERELVAKQEPEKTLDTAEPEPEHNFLTPE 677
            :...|....|....||..|.|      :|:..:   |.:...:|:.||   ...||........:
 Frog   809 KSSSAAATRETNPHLSVQKNS------LPKTND---EVDFALEQKNEK---NRNPECVDKINASD 861

  Fly   678 Q---SPKEFQTNGSGSGSGERWEKRLGKFKYGNKRDKYNNDNDS---NSPSPKS----------- 725
            .   |....::.||                  :|.:.|...|.|   :||:|.|
 Frog   862 AIKISTVSLESQGS------------------DKANHYTPINSSLGYSSPTPASLPTDKCTTPSA 908

  Fly   726 ---TERIIIGHEKSGSHADRR--------SE------------ISAQL----------------- 750
               |:..|.|.:|..|...::        ||            :|:::
 Frog   909 DPPTKPAIEGTDKVDSSGKKKLLRAWVSPSETHPIPTVQSGGTVSSRIRTNPVKPMSATQTKTVS 973

  Fly   751 ------------AKKYEGK---------SREELMLIANGMENEALLQRQRV--KELEDYLDNLLL 792
                        .|||:..         :.:||:.:.  ::.:.::.::.|  :|||||:||||:
 Frog   974 GFSQPIKSHDVAIKKYDPTDPAAAYSQLTHDELIQLV--LKQKDIISKKEVQMRELEDYIDNLLV 1036

  Fly   793 RVMETHPKILQNPYSRTTSAKRYGTW 818
            |:||..|.:||      :..|:.|.|
 Frog  1037 RIMEETPSLLQ------SINKKMGKW 1056

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rip11	NP_573313.2	C2_Rab11-FIP_classI	7..130	CDD:176064	54/127 (43%)
		RBD-FIP	758..805	CDD:255374	18/48 (38%)
rab11fip1	XP_012814911.2	C2_Rab11-FIP_classI	15..140	CDD:176064	54/127 (43%)
		rad2	<279..>703	CDD:273166	86/458 (19%)
		RBD-FIP	1002..1047	CDD:401421	16/46 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7659
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D259412at33208
OrthoFinder	1	1.000	-	-		FOG0002878
OrthoInspector	1	1.000	-	-		otm48812
Panther	1	1.100	-	-	LDO	PTHR15746
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X973
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.020