Protein Alignment Rip11 and Rab11fip5

DIOPT Version :10

• Sequence 1: NP_573313.2
• Gene: Rip11 / 32850
• FlyBaseID: FBgn0027335
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: NP_001003955.1
• Gene: Rab11fip5 / 52055
• MGIID: 1098586
• Length: 1318
• Species: Mus musculus
• Alignment Length: 1333
• Identity: 290/1333 - (21%)
• Similarity: 411/1333 - (30%)
• Gaps: 568/1333 - (42%)

  Fly     2 WSPTHCSVTVQRARGLLTK--GKNGTNNCFVTIALGKEKYQTSVKDKAETSVNWNEECELKIP-- 62
            |.|||..|||.||.||..|  |...|::.:..|.:|:|||.|||.:|.:....|.|||..::|
Mouse    16 WLPTHVQVTVLRASGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTQGCPEWCEECSFELPPG 80

  Fly    63 -----------DQG--------NRA-ELTLTCLHRNNLGIDEFLGQATLPLNEMDVYDRPRA--- 104
                       |.|        |.| ||.||.:||:.:|:|:|||:||:.|:|  |:...||
Mouse    81 ALDGLLRAQEADAGPAPWASGPNAACELVLTTMHRSLIGVDKFLGRATVALDE--VFRAGRAQHT 143

  Fly   105 KWFKLESKPGKEKKNKERGELEVRIAFVVK--SGSLTDLSKKDKHKSSIGQLASSVGG------- 160
            :|::|.||||  ||.|||||::|.|.|...  |.|:.|||.|||.:|...:|...|.|
Mouse   144 QWYRLHSKPG--KKEKERGEIQVTIQFTRNNLSASMFDLSMKDKPRSPFSKLKDRVKGKKKYDLE 206

  Fly   161 --------------SLLSIGNGEKRRG------------------------IKKLAGSL------ 181
                          .|.|:|...|.:|                        :...:|||
Mouse   207 SASAILPSSALEDPELGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSTSGSLVYQGPG 271

  Fly   182 ------------------------SSKLHIRSKKKNQEA-------------------GADDS-- 201
                                    |.||....:..:.||                   ||..|
Mouse   272 AELLTRSPSHSSWLSTEGGRDSIQSPKLLTHKRTYSDEASQLRAAPPRALLELQGHLDGASRSSL 336

  Fly   202 -------------------SSFGGSF---ASLGT--PNSS--NGRGQNGGSGRRRGGQRAGEADP 240
                               ||..|.|   :||.:  |.||  ..|..:...||...|..:.||.|
Mouse   337 CVNGSHVYNEEPQPPLRHRSSISGPFPPSSSLHSVPPRSSEEGSRSSDDSWGRGSHGTSSSEAVP 401

  Fly   241 GVISEDEDEFVFDNLSHKSSGSSLNIQRIGL-----QPPPVGTPN-------------------F 281
            |.          :.||.::.|:|.:.:..|.     :|..|.||.                   |
Mouse   402 GQ----------EELSKQAKGASCSGEEEGARLPEGKPVQVATPMVASSEAVAAEKDRKPRMGLF 456

  Fly   282 TPRHPSPLLNNGVSGVGSGSAKGKQAV-----LPATLDEDA-----------------SIDAEME 324
            ...|...|..:.....||...||..::     ..:|.:|.|                 |:|.. .
Mouse   457 HHHHHQGLSRSEQGRRGSVGEKGSPSLGASPHHSSTGEEKAKSSWFGLRESKEPTQKPSLDVS-P 520

  Fly   325 QLELD----------------------------FSVRAHARANA-------NASASGNASTLPP- 353
            |:|.|                            |:|.:.|.|.|       .|:.||......|
Mouse   521 QVESDPAAPHPCSPQALAPPPAPAAAPMLSTNLFAVTSPAAATAAAATIVLEATPSGFLGVTNPF 585

  Fly   354 ---------------------PSKPPRIP-LSQVDEQP------------------AAGSLERE- 377
                                 ||..|.:| .|:....|                  |||.|::|
Mouse   586 LNSLQSNPFFEDLKADIALNSPSPAPSLPSASRASLAPLASPGKALPEWDDTFNIFAAGRLQQEA 650

  Fly   378 ------------------------------KPKEKP--------------AEVESDKDEWASKLY 398
                                          :|:.:|              ..|:|:.|:.::.:.
Mouse   651 GSGILAPAGMGLEEDGLQDPGPRTMAVKATEPQGEPGRGRRGSNIWLEPKVSVDSELDQPSTSMS 715

  Fly   399 GGGKYLEIGSSNSLKRRSWEDRVPLPASVEEP-------------PPLHSSSSSSSSSS------ 444
            ..|.:...||..|    |...::.|.||...|             .|..|.:|..||..
Mouse   716 DPGPFGSSGSGPS----SRASQLHLQASASTPDRELPASEGGAGQSPADSGASLFSSPEVLSVWE 776

  Fly   445 ---DSDDD----DEKPPQ---------------------------AAPPPVPVPASLPVPSAAAS 475
               .|||.    ||:.||                           ....||....|..|.|:...
Mouse   777 RFPGSDDTPGGRDEEAPQDGSQLFQELNTVEDSWPWDVITISPTAEVASPVMKGESDGVLSSQVQ 841

  Fly   476 TASADPVVATSS----SLFSPDVEH----------------RNFDTFNASFA---KYEQRNST-- 515
            ..|.|.|....|    :|..|:.|.                |.|...|:...   |.|:.|:|
Mouse   842 PESPDTVPPMGSEGLPALLEPEPEQGLDEGPWLGPPPPKPPRLFTPTNSQVEEEDKEEEENATGR 906

  Fly   516 -----------------AIFADE------------------------PELEDLTVELEKPA---- 535
                             ||...|                        |||||...|...|.
Mouse   907 QSSRGPGVEKDSTPRALAIGPQESKEEWVNPELEKLHRLPSGTLIGKPELEDPVGETSSPVFGDC 971

  Fly   536 -PTPTARPK-PQPRATADL-----------RAEEEKAKEEAARQLRAEEDARLEAELRLNEERLR 587
             |.||:.|: |.||....:           .:|.|:..|..:::|..|....|....:.:..|.:
Mouse   972 PPRPTSCPEGPVPRPHNSISSTLLSQKVLGTSETEEGFETKSQELAKEGFGPLSVPSQQSSMRAK 1036

  Fly   588 EEEEAMQRELEEEKERQKQLQMDEQQRREAKRWEEDQRLLSF------AKRSTSL-----EEPVP 641
            ||||.  .|.|||.|.::.|:..     .:...:|.|...||      ..|.:|:     |.|.|
Mouse  1037 EEEEG--EEEEEEGEEEEALETS-----NSFLCQESQDPPSFPSISPPGSRGSSIHSGPEELPTP 1094

  Fly   642 EKQEL---------KHERELVAKQEPEKTLD---TAEPEPEHNFLTPEQSPKEFQTNGSGSGSGE 694
            .:...         .|...:.....|...:.   |:...|.....:|...|:...|.||.:..||
Mouse  1095 PEPAFPPPPLPPWASHRHGVPGPPCPPLPIAWPLTSSSSPPEESASPLGPPELSPTGGSPTSYGE 1159

  Fly   695 --------------RWEKRLGKFKYGNKRDKYNNDNDSNSPSP---------------------- 723
                          ..|.|..:           ....|.||.|
Mouse  1160 DHAAATPASPLVLLPLETRPAE-----------EPQPSGSPHPVKPLTAAPVEASPDRKQPRTSL 1213

  Fly   724 -----KSTERI----------IIGHEKSGSHAD-RRSEISAQL--AKKYEGKSREELMLIANGME 770
                 ...||:          ::...:.||..| :|.:.||.|  :.||...:.:||:.:....|
Mouse  1214 STALSSGLERLKTVTSGGIQSVLPASQLGSSVDTKRPKDSAVLDQSAKYYHLTHDELIGLLLQRE 1278

  Fly   771 NEALLQRQRVKELEDYLDNLLLRVMETHPKILQ 803
            .|...:.:.|:|||.|:|.||:|:|||.|.:||
Mouse  1279 RELSQRDEHVQELESYIDRLLVRIMETSPTLLQ 1311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rip11	NP_573313.2	C2_Rab11-FIP_classI	7..130	CDD:176064	60/149 (40%)
		RBD-FIP	758..805	CDD:462805	19/46 (41%)
Rab11fip5	NP_001003955.1	C2	21..167	CDD:472691	60/149 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..299		1/27 (4%)
		RBD-FIP	1266..1312	CDD:462805	19/46 (41%)