Protein Alignment Rip11 and Rab11fip1

DIOPT Version :10

• Sequence 1: NP_573313.2
• Gene: Rip11 / 32850
• FlyBaseID: FBgn0027335
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: NP_001178484.1
• Gene: Rab11fip1 / 498650
• RGDID: 1562965
• Length: 1189
• Species: Rattus norvegicus
• Alignment Length: 1252
• Identity: 268/1252 - (21%)
• Similarity: 387/1252 - (30%)
• Gaps: 533/1252 - (42%)

  Fly     1 MWSPTHCSVTVQRARGLLTKGKNGTNNCFVTIALGKEKYQTSVKDKAETSVNWNEECELKIP--- 62
            ||||||..|||.:||||..||..||::.:..|.:|||||.|||.:::..:..|.||...::|
  Rat    14 MWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPPLL 78

  Fly    63 DQGN-----RAELTLTCLHRNNLGIDEFLGQATLPLNEMDVYDRPRAK--WFKLESKPGKEKKNK 120
            ..|.     .|.|.||.|||..||:|:|||:|.:.|.|:. .|:.|.|  |:.|:||||  ||:|
  Rat    79 SSGTAPAAAAATLQLTVLHRALLGLDKFLGRAEVDLRELH-RDQSRRKKQWYTLKSKPG--KKDK 140

  Fly   121 ERGELEVRIAFVVK--SGSLTDLSKKDKHKSSIGQLASSVGG----------------SLLSIGN 167
            ||||:||.|.|:..  :.|:.|||.|||.::..|:|...:.|                :..|:.:
  Rat   141 ERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDNTSDTASAIVPSTTPSVDS 205

  Fly   168 GE--------KRRGIKKLAGS-------LSSKLHI----------------RSKKKNQEAGADDS 201
            .:        |:..||.|...       ||..:.:                :|:..::....|:|
  Rat   206 DDESFSKDKKKKSKIKTLFSKPSLQKTPLSQSMSVLPTSKPDKVLLRPGDFQSRWGDEGDNEDES 270

  Fly   202 SSFGGSFASLGT-------PNSSNG--------------RGQNGGSGRRR---GGQRAGEADPGV 242
            ||.....:...|       ||.||.              |.:|....|..   .|.......|..
  Rat   271 SSASEVMSQKRTSSTDHTQPNQSNFSLPKKEGLSFLGGLRSKNDSLSRSNVCINGNHVYMEQPEA 335

  Fly   243 ISEDEDEFVFDNLSHKSSGSSLNIQRIGLQPPPVG---------TPNFTPRHPSPLLNNGVSGVG 298
            .||          ..:||.|:        .|.|.|         |.|...|.|..      .|.|
  Rat   336 KSE----------IRESSPSN--------SPSPQGFRKRHLFSSTENLAARSPKE------PGEG 376

  Fly   299 SGSAKGKQAVLPATLDEDASIDAEMEQLELDFSVRAHARANANASASGNASTLPPPSKPPRIPLS 363
            .|.:..::.       .|:|....|:.:.|                            |...||:
  Rat   377 GGMSSDRRL-------SDSSTKDSMKSMSL----------------------------PSYRPLT 406

  Fly   364 QVDEQ----PAAGSLEREKPKEKPAEVESDKDEWASKLYGGGKYLEIGS---------------- 408
            ..|.:    ||...:..::.|:...: ||.|....| |..|.|.:..||
  Rat   407 TADSREGLSPANMEVATKETKDSKKQ-ESKKSSLLS-LVTGKKDVAKGSEGEPLPPVSEKEKGRK 469

  Fly   409 ---------SNSLKRRSWEDRVPLPAS-VEEPPPLHSSSSSSSSSSDSDDDDEKPPQAAP----- 458
                     ...|.||..:|.||:.:. .....|...:..|...:|.....:.|||...|
  Rat   470 GVLVEAQLREEDLVRRPEKDAVPVASQWGSSQNPFEDAQISDLEASVESKCEPKPPVPVPRTPQT 534

  Fly   459 --------------PPVPVPASLPVPSAAASTASAD-PVVA--------------TSSSLFSP-- 492
                          |...:|:|...|.||..::||. ||::              ::||..||
  Rat   535 RAVKPRLEVSPEAQPKARLPSSDSAPFAAFLSSSAQAPVLSDLRCDSETQFSESPSASSFSSPLA 599

  Fly   493 -------DVEHRNFDTFNASFAKYEQRNSTAIFADEPELEDLTVELEKPA--------------- 535
                   .|||...|...|.             |:||.|....:....||
  Rat   600 APISTSTPVEHWPTDKGEAD-------------AEEPSLLLRAISSVTPAANAGSSASRSPCEQL 651

  Fly   536 PTPTARPKPQPRATADLRA----------EEEKA----KEE------------------AARQLR 568
            ||| .|..||..:....|.          |.||:    .||                  |...::
  Rat   652 PTP-ERKGPQESSGGKARESGTGKEVGSDESEKSLIGQHEELLKIPFPERHWALGGMTTATSPVQ 715

  Fly   569 AEEDARLEAELRLNEERLREEEEAMQRELEEEKERQKQLQMDEQQRREAKRWEED------QRLL 627
            .||.|.....:|...:.:.:.....||:.::.....:||.::|:  .|...|.|:      |:|.
  Rat   716 EEEAASSFHSVRPKHQEMHQNASGGQRKAKKRVSFSEQLFVEEE--TEGPTWLEEGDKGHPQQLS 778

  Fly   628 SFAKRSTSL---------------EEPV---------------------------PEKQEL---- 646
            .....::|:               :|||                           .||.:|
  Rat   779 QEGPVASSMPSAGSPESPHTEGTGQEPVTISSESESFLEGPQSEASPARGTQLLRDEKDDLMAPC 843

  Fly   647 -----KHE-----------------------------------------------------RELV 653
                 .||                                                     .:|.
  Rat   844 QSKASDHEGLLSNPLSDLPSASDLKSPIMADLSLSLPSIPEVASDDERFDETGDGGKGARLADLE 908

  Fly   654 AKQEP----EKTLDTA--------EPEPEHNFL-----TPEQSPKEFQTNGSGSGSGERWEKRLG 701
            |...|    ...|:||        |..|..|..     ||:.:|.| ||...||.     :..||
  Rat   909 AGVSPLNVSPSILETAGQTGGRAHESVPVENQCDLRPQTPKAAPSE-QTAALGSP-----KPHLG 967

  Fly   702 KF-----KY------------GNKRDKYNNDNDSNSPS---------------PKSTERIIIGHE 734
            |.     :|            |:.|.....|:...|||               |..|....:...
  Rat   968 KSSSVNEEYPGPDTVDEEKLKGSGRPGSPLDSPVRSPSLAETFPATHSFPGSPPSDTHHTTVAES 1032

  Fly   735 KSGSHADRRSE-----------------------ISAQ--------------------LAKKYEG 756
            :..:.||..|.                       :.||                    .|.|...
  Rat  1033 QKQATADVSSNRVENFGKKKPLLQAWVTPSEIHPVPAQPSAGAGAAKHRPHPVKPMNTTAPKITN 1097

  Fly   757 KSREELMLIANGMENEALLQRQ---------------------------------RVKELEDYLD 788
            .|.....:|:..:.||||:::.                                 :|:|||||:|
  Rat  1098 SSLGTATIISENLINEALMKKYQPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYID 1162

  Fly   789 NLLLRVMETHPKILQNP 805
            |||:||||..|.||:.|
  Rat  1163 NLLVRVMEETPNILRVP 1179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rip11	NP_573313.2	C2_Rab11-FIP_classI	7..130	CDD:176064	59/132 (45%)
		RBD-FIP	758..805	CDD:462805	23/79 (29%)
Rab11fip1	NP_001178484.1	C2_Rab11-FIP_classI	20..150	CDD:176064	59/132 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	164..470		64/366 (17%)
		PTZ00449	<423..796	CDD:185628	76/390 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	483..503		5/19 (26%)
		PHA03307	757..>1082	CDD:223039	49/332 (15%)
		RBD-FIP	1132..1179	CDD:462805	17/46 (37%)