Protein Alignment Rip11 and Rab11fip5

DIOPT Version :10

• Sequence 1: NP_573313.2
• Gene: Rip11 / 32850
• FlyBaseID: FBgn0027335
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: XP_038964650.1
• Gene: Rab11fip5 / 312502
• RGDID: 1592069
• Length: 1317
• Species: Rattus norvegicus
• Alignment Length: 1338
• Identity: 286/1338 - (21%)
• Similarity: 416/1338 - (31%)
• Gaps: 579/1338 - (43%)

  Fly     2 WSPTHCSVTVQRARGLLTK--GKNGTNNCFVTIALGKEKYQTSVKDKAETSVNWNEECELKIP-- 62
            |.|||..|||.||.||..|  |...|::.:..|.:|:|||.|||.:|.:....|.|||..::|
  Rat    16 WLPTHVQVTVLRASGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTQGCPEWCEECSFELPPG 80

  Fly    63 -----------DQG--------NRA-ELTLTCLHRNNLGIDEFLGQATLPLNEMDVYDRPRA--- 104
                       |.|        |.| ||.||.:||:.:|:|:|||:||:.|:|  |:...||
  Rat    81 ALDGLLRAQETDAGPAPWASGPNAACELVLTTMHRSLIGVDKFLGRATVALDE--VFRAGRAQHT 143

  Fly   105 KWFKLESKPGKEKKNKERGELEVRIAFVVK--SGSLTDLSKKDKHKSSIGQLASSVGG------- 160
            :|:||.||||  ||.|||||::|.|.|...  |.|:.|||.|||.:|...:|...|.|
  Rat   144 QWYKLHSKPG--KKEKERGEIQVTIQFTRNNLSASMFDLSMKDKPRSPFSKLKDKVKGKKKYDLE 206

  Fly   161 --------------SLLSIGNGEKRRG------------------------IKKLAGSL-----S 182
                          .|.|:|...|.:|                        :...:|||     .
  Rat   207 SASAILPSSALEDPELGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSTSGSLVYQGPG 271

  Fly   183 SKLHIRSKKKNQ----EAGADD------------------------------------------- 200
            ::|..||...:.    |||.|.
  Rat   272 AELLTRSPSHSSWLATEAGRDSIQSPKLLTHKRTYSDEASQLRAAPPRALLELQGHLDGASRSSL 336

  Fly   201 ------------------SSSFGGSFASLG----TPNSSNGRGQNGGSGRRRG--GQRAGEADPG 241
                              .||..|.|.|..    .|.||....::......||  |..:.||.||
  Rat   337 CVNGSHVYNEEPQPPLRHRSSISGPFPSSSLHSVPPRSSEEGSRSSDDSWVRGSHGTSSLEAVPG 401

  Fly   242 VISEDEDEFVFDNLSHKSS----GSSLNIQRIGLQPP-----PVGTPN----------------- 280
            .          :.||.::.    |:|.:.:..|.:||     .|.||.
  Rat   402 Q----------EELSKQTKVLAPGASCSAEEEGTRPPEGKPVQVATPMVASSEAIAAEKERKPRM 456

  Fly   281 --FTPRHPSPLLNNGVSGVGSGSAKGKQAV-----LPATLDEDA-----------------SIDA 321
              |...|...|..|.|...||...||..::     ..:|.:|.|                 |:|.
  Rat   457 GLFHHHHHQGLSRNEVGRRGSVGEKGSPSLGASPHHSSTGEEKAKSSWFGLRESKEPTQKPSLDV 521

  Fly   322 EMEQLELD----------------------------FSVRAHARANANASA-------------- 344
            . .|:|.|                            |:..:.|.|.|.|:|
  Rat   522 S-PQVESDPAAPHPCFPQALVPPPAPAAAPMLSTNLFAAASPATATATAAAANIVLEATPSGFLG 585

  Fly   345 ----------------------------------SGNASTLPPPSKP------------------ 357
                                              |.:.::|.|.:.|
  Rat   586 VTNPFLTSLQSNPFFEDLKADIALNSPSPAPSLPSASRASLAPLASPGKALPEWDDNFNIFAAGR 650

  Fly   358 -----------------------------------------------------PRIPLSQVDEQP 369
                                                                 |:.|:..|.:||
  Rat   651 LQSEAGSGILAPAGMGLEEDGLQDPGPRTLAVKATEPQGEPGGGRGGSSTWLEPKAPVDSVLDQP 715

  Fly   370 ----------------------------AAGSLEREKPKEKPAEVESDKDEWASKLYGGGKYLEI 406
                                        :|.:.:||.|..:....:|..|..|| |:...:.|.:
  Rat   716 STSMSDPGPLGSSGTGPSSRAAQLHLQASASTPDRELPASEGGAGQSPADSGAS-LFSSPEVLSV 779

  Fly   407 -----GSSNS---LKRR-----------------SWE-DRVPLPASVEEPPPLHSSSSSS--SSS 443
                 ||.::   |:..                 ||. |.:.:..:.|...|:....|..  ||.
  Rat   780 WERFPGSDDTPGGLEEEAAQDGSQLFQELNTVEDSWPWDVITISPTAEAASPVMKGESKGVLSSQ 844

  Fly   444 SDSDDDDEKPP---------QAAP-------------PPVPVPASLPVP-------------SAA 473
            ...:..|..||         |..|             ||.|.|..|..|             :|.
  Rat   845 VQPEYPDTVPPMGSEGLPSLQLEPEPEQGLDEGPWLGPPPPKPPRLFTPTNSQVEEDKEEEENAT 909

  Fly   474 ASTASADPVV--ATSSSLFSPDVEHRNFDTFNASFAKYEQRNSTAIFADEPELEDLTVELEKPA- 535
            ...:|..|.|  :|.|:|.....|.:. :..|:...:..:..|..:.. ||||||:..|...|.
  Rat   910 GGPSSRGPGVEDSTPSALVIGPPESKE-EGVNSELEELHRLPSGTLIG-EPELEDVVGETSSPGS 972

  Fly   536 ----PTPTARPK-PQPR----ATADL-------RAEEEKAKEEAARQLRAEEDARLEAELRLNEE 584
                |.||:.|: |.||    |::.|       .:|.:::.|..:::|..|....|....:..:.
  Rat   973 RDCLPRPTSCPEGPIPRSHNSASSTLLSQKDWGTSETDESFETQSQELAKEGFGALSVPSQQADL 1037

  Fly   585 RLREEEEAMQRELEEEKERQKQLQMDEQQRREAKRWEEDQRLLSFAKRSTSLEEPVPEKQELKHE 649
            .:::|||..::|.|||         :|::.......:|.|..||..  |||   |...:....|.
  Rat  1038 WVKKEEEEEEKEAEEE---------EEEEASNPFSCQESQDPLSLP--STS---PPGSRGSSTHS 1088

  Fly   650 --RELVAKQEPEKTLDTAEPEPEHNF---------------LT-----PEQS--PKEFQ-TNGSG 689
              .||....||........|...|..               ||     ||:|  |.|.. |.||.
  Rat  1089 GPEELPTPPEPAFPPPPLPPWASHRHGVPGPPCPPLPIAWPLTSSSSLPEESACPLELSPTGGSP 1153

  Fly   690 SGSGE--------------RWEKRLGKFKYGNKRDKYNNDNDSNSPSP----------------- 723
            :..||              ..|.|..:           :...|.||.|
  Rat  1154 TPYGEDHAAATPASPLVLLPLETRPAE-----------DPQPSGSPHPVKPLTAAPVEASPDRKQ 1207

  Fly   724 ----------KSTERI----------IIGHEKSGSHAD-RRSEISAQL--AKKYEGKSREELMLI 765
                      ...||:          ::...:.||..| :|.:.||.|  :.||...:.:||:.:
  Rat  1208 SRTSLSTALSSGLERLKTVTSGGIQSVLPASQLGSTVDTKRLKDSAVLDQSAKYYHLTHDELIGL 1272

  Fly   766 ANGMENEALLQRQRVKELEDYLDNLLLRVMETHPKILQ 803
            ....|.|...:.:.|:|||.|:|.||:|:|||.|.:||
  Rat  1273 LLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQ 1310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rip11	NP_573313.2	C2_Rab11-FIP_classI	7..130	CDD:176064	61/149 (41%)
		RBD-FIP	758..805	CDD:462805	19/46 (41%)
Rab11fip5	XP_038964650.1	C2	21..167	CDD:472691	61/149 (41%)
		RBD-FIP	1265..1311	CDD:462805	19/46 (41%)