DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and LPXN

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001137467.1	Gene:	LPXN / 9404	HGNCID:	14061	Length:	391	Species:	Homo sapiens

Alignment Length:	148	Identity:	43/148 - (29%)
Similarity:	65/148 - (43%)	Gaps:	13/148 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEV--GSTLYTKGNLMLCKRDYLRLFG 151
            |..||.|...|.|: :|.|::..||.:...|..|    |||  ....:.|.....|::|:|.:|
Human   213 SPRCAYCAAPILDK-VLTAMNQTWHPEHFFCSHC----GEVFGAEGFHEKDKKPYCRKDFLAMF- 271

  Fly   152 NTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERL-V 215
             :..|..|::  |..|..:.|...|:|.|||.|..|...|..|. |:..:.:..||..|..|. .
Human   272 -SPKCGGCNR--PVLENYLSAMDTVWHPECFVCGDCFTSFSTGS-FFELDGRPFCELHYHHRRGT 332

  Fly   216 FASMANHPMLKRHVSSLG 233
            .......|:..|.:|::|
Human   333 LCHGCGQPITGRCISAMG 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	16/55 (29%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	17/53 (32%)
LPXN	NP_001137467.1	LIM1_Leupaxin	155..209	CDD:188790
		LIM2_Leupaxin	216..267	CDD:188792	16/55 (29%)
		LIM3_Leupaxin	275..327	CDD:188794	17/54 (31%)
		LIM4_Paxillin_like	334..385	CDD:188725	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920