DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Bx and ISX

DIOPT Version :9

Sequence 1:NP_001259687.1 Gene:Bx / 32846 FlyBaseID:FBgn0265598 Length:424 Species:Drosophila melanogaster
Sequence 2:NP_001290437.1 Gene:ISX / 91464 HGNCID:28084 Length:245 Species:Homo sapiens


Alignment Length:88 Identity:21/88 - (23%)
Similarity:31/88 - (35%) Gaps:18/88 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   184 CQQCNHRFCVGDRFYLCENKI-LCEYDYEERLVFASMANHPMLKRHVSSLGQGSPTGAAGAQNTA 247
            |.:.....|.|    :..|.: .||...:..|.|:..|   :|||.........|.| .|.:   
Human     2 CAEVGPALCRG----MERNSLGCCEAPKKLSLSFSIEA---ILKRPARRSDMDRPEG-PGEE--- 55

  Fly   248 GGLLGGGPGGGNVNGVGMVNGPR 270
                  |||....:|.|:...|:
Human    56 ------GPGEAAASGSGLEKPPK 72

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BxNP_001259687.1 LIM1_LMO1_LMO3 92..146 CDD:188774
LIM2_dLMO 156..210 CDD:188776 6/26 (23%)
ISXNP_001290437.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 38..86 11/45 (24%)
Homeobox 86..138 CDD:278475
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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