DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and RGA2

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_010667.1	Gene:	RGA2 / 851985	SGDID:	S000002787	Length:	1009	Species:	Saccharomyces cerevisiae

Alignment Length:	130	Identity:	31/130 - (23%)
Similarity:	51/130 - (39%)	Gaps:	9/130 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 NNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLF 150
            |:.|.||..|.|.|....:.......||:.|..|..||.:|......|......::|       :
Yeast     7 NDQSSLCVRCNKSIASSQVYELESKKWHDQCFTCYKCDKKLNADSDFLVLDIGTLIC-------Y 64

  Fly   151 GNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLV 215
            ..:..|..|...|....:::.:....|...||.|.:|::|  :.:..|....:.||..|..|:|:
Yeast    65 DCSDKCTNCGDKIDDTAIILPSSNEAYCSNCFRCCRCSNR--IKNLKYAKTKRGLCCMDCHEKLL 127

Fly 216 215
Yeast 128 127

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	13/53 (25%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	12/53 (23%)
RGA2	NP_010667.1	LIM1_Rga	13..67	CDD:188780	13/60 (22%)
		LIM2_Rga	70..123	CDD:188781	13/54 (24%)
		RhoGAP	815..1002	CDD:214618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2809
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950