DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and Tgfb1i1

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_006230411.1	Gene:	Tgfb1i1 / 84574	RGDID:	620173	Length:	473	Species:	Rattus norvegicus

Alignment Length:	147	Identity:	42/147 - (28%)
Similarity:	70/147 - (47%)	Gaps:	9/147 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNT 153
            |..|..|.:.|:.: ::.||...||.:...|..|....||.|  .:.:.....|:||:|:||...
  Rat   296 SPRCGFCNQPIRHK-MVTALGTHWHPEHFCCVSCGEPFGEEG--FHEREGRPYCRRDFLQLFAPR 357

  Fly   154 GYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCE-YDYEERLVFA 217
              |..|..  |..:..:.|.:.::|.:||.|::|...|. |..|:..|.:.||| :.:.:|....
  Rat   358 --CQGCQG--PILDNYISALSALWHPDCFVCRECLAPFS-GGSFFEHEGRPLCENHFHAQRGSLC 417

  Fly   218 SMANHPMLKRHVSSLGQ 234
            :....|:..|.||:||:
  Rat   418 ATCGLPVTGRCVSALGR 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	14/53 (26%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	16/54 (30%)
Tgfb1i1	XP_006230411.1	Paxillin	<69..>118	CDD:281527
		LIM1_Paxillin_like	240..292	CDD:259830
		LIM2_Paxillin_like	299..350	CDD:188723	14/53 (26%)
		LIM3_Paxillin	358..410	CDD:188793	16/54 (30%)
		LIM4_Leupaxin	417..468	CDD:188796	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920