DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and LHX3

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_055379.1	Gene:	LHX3 / 8022	HGNCID:	6595	Length:	402	Species:	Homo sapiens

Alignment Length:	122	Identity:	56/122 - (45%)
Similarity:	75/122 - (61%)	Gaps:	6/122 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 LCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGY 155
            |||||.:||.||::|:|||..||..||||..|...|.|   ..:::|..:.||.|:.:.||..
Human    35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFGTK-- 94

  Fly   156 CAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCE-NKILCEYDYE 211
            ||||...||..::|.||:..||||.||||..|..:...||.|||.| ::::|:.|||
Human    95 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	24/53 (45%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	25/54 (46%)
LHX3	NP_055379.1	LIM1_Lhx3b	33..87	CDD:188851	25/54 (46%)
		LIM2_Lhx3_Lhx4	95..150	CDD:188762	25/54 (46%)
		Homeobox	165..218	CDD:278475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910