Protein Alignment Bx and lhx2b

DIOPT Version :10

• Sequence 1: NP_001259687.1
• Gene: Bx / 32846
• FlyBaseID: FBgn0265598
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001035099.3
• Gene: lhx2b / 791744
• ZFINID: ZDB-GENE-051220-1
• Length: 427
• Species: Danio rerio
• Alignment Length: 276
• Identity: 91/276 - (32%)
• Similarity: 115/276 - (41%)
• Gaps: 57/276 - (20%)

  Fly    49 NGNVVNVVNSG------GAGGG----------NNGNGNVQSIAAAANNNNNNNNNGS------QL 91
            :||....|:|.      |..||          ..|..:..:|::|.:......|..|      .|
Zfish    19 DGNTCYSVSSAATMLFHGLPGGEMHGVMEEMERRGKSDSATISSAIDMGETETNMPSISGDRVAL 83

  Fly    92 CAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLG-EVGSTLYTKGNLMLCKRDYLRLFGNTGY 155
            |||||..|.|||.|.|:|..||..|||  ||:|:|. |...|.::|...:.||.||.|.| :...
Zfish    84 CAGCGGKISDRYYLLAVDKQWHMRCLK--CCECKLNLESELTCFSKDGSIYCKEDYYRRF-SVQR 145

  Fly   156 CAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLV--FAS 218
            ||.|...|.|.|||||||..||||.||.|..||.....||.|.:.::.:.|...:|..:.  |.:
Zfish   146 CARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFETLIQGDFPT 210

  Fly   219 MANHPMLKRHVSSLGQGSPTGAAGAQNTAGGLLGGGP-GGGNVNGVGMVNGPRTPGDHNNNNNGP 282
            ..||..:                 |.|.  ||...|| |....|||..|...|   .....:.||
Zfish   211 HFNHTDV-----------------APNK--GLSSTGPLGLSYYNGVNTVQKGR---PRKRKSPGP 253

  Fly   283 QTPTGGGSPFAAAAAA 298
                  |:..||..||
Zfish   254 ------GADLAAYNAA 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	26/54 (48%)
		LIM2_dLMO	156..210	CDD:188776	25/53 (47%)
lhx2b	NP_001035099.3	LIM1_Lhx2	74..137	CDD:188853	28/64 (44%)
		LIM2_Lhx2_Lhx9	142..200	CDD:188763	25/57 (44%)
		COG5576	<267..389	CDD:227863
		Homeodomain	287..343	CDD:459649