Protein Alignment Bx and lhx4

DIOPT Version :10

• Sequence 1: NP_001259687.1
• Gene: Bx / 32846
• FlyBaseID: FBgn0265598
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001116445.1
• Gene: lhx4 / 571943
• ZFINID: ZDB-GENE-060728-1
• Length: 391
• Species: Danio rerio
• Alignment Length: 343
• Identity: 88/343 - (25%)
• Similarity: 130/343 - (37%)
• Gaps: 114/343 - (33%)

  Fly    92 CAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYC 156
            ||||.:||.|:::|:.||..||..||||..|...|.:   ..:::...:.||.|:.:.||..  |
Zfish    33 CAGCSQHILDKFILKVLDRHWHSKCLKCADCHALLAD---KCFSRAGNVYCKEDFFKRFGTK--C 92

  Fly   157 AACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCEN-KILCEYDYEE-------- 212
            |:|.:.||..::|.:|:..||||.||||..|:.:...||.|||.|: :::|:.|||.
Zfish    93 ASCQQGIPPTQVVRKAQDFVYHLHCFACVMCSRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSE 157

  Fly   213 ---------------RLVFASMANHPMLKRHVSS------------------------------- 231
                           ..:.::..|.|...|||..
Zfish   158 TGAKRPRTTITAKQLETLKSAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDA 222

  Fly   232 ----LGQ----------GSPTGAAGAQNTAG-----------GLLGGGPGGGNVNGV-GMVNGPR 270
                .||          .|.|....:.:.||           .:|.   ..|:.||: |.|
Zfish   223 GRHRWGQFYKSVKRNRGSSKTEKESSADDAGLSDSELSFRDDQILS---DLGHANGLYGSV---- 280

  Fly   271 TPGDHNNNN--NGPQTPTGGGSPF------------AAAAAAAAAAAH--MKNQLGASSXNKALG 319
              ||.:|.|  ||..:..|||.|:            .:.::..:...|  :.|.||.|. ..
Zfish   281 --GDVSNGNMLNGSFSLDGGGQPYHDLRAGSPYGLPQSPSSITSLPGHTPLLNNLGFSMDGL--- 340

  Fly   320 MGAAGAVVPGSGVGAGVG 337
            ||.||....|..:.|..|
Zfish   341 MGQAGQPSVGQALRAMAG 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	20/53 (38%)
		LIM2_dLMO	156..210	CDD:188776	23/54 (43%)
lhx4	NP_001116445.1	LIM1_Lhx4	33..84	CDD:188852	20/53 (38%)
		LIM2_Lhx3_Lhx4	92..147	CDD:188762	23/54 (43%)
		Homeodomain	161..217	CDD:459649	5/55 (9%)