DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bx and wtip

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001116750.2	Gene:	wtip / 566046	ZFINID:	ZDB-GENE-050419-261	Length:	648	Species:	Danio rerio

Alignment Length:	313	Identity:	73/313 - (23%)
Similarity:	113/313 - (36%)	Gaps:	104/313 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TEPGLVGLSSNQ--------QQQQQQQSQQSNAGMN-----SGGQ------------NNGPNPNG 48
            |||.  ||.:|:        .::.|||:.:.|.|.|     :|||            ::||:...
Zfish   351 TEPN--GLHNNRVHLQTFPVLEEPQQQNSEVNIGFNYCKAGAGGQRFKLPYQVTPSRDSGPSQAE 413

  Fly    49 N----------------------GNVVNVVNSGGAGGGNNGNGNVQSIAAAANNNNNN------- 84
            .                      |..|..        |....|..|:..|..|..:.|
Zfish   414 RRLEALTLELEKELEIHMKKEYFGICVKC--------GKGVYGASQACQAMGNLYHTNCFTCCSC 470

  Fly    85 ----------NNNG----------------SQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCD 123
                      |.||                ::.|..|| |:....:|:||...:|..|.:|..|.
Zfish   471 GRRLRGKAFYNVNGKVYCEEDFLYSGFQQTAEKCFVCG-HLIMEMILQALGRSYHPGCFRCVICK 534

  Fly   124 CRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYCAACSK-VIPA--FEMVMR--ARTNVYHLECFA 183
            ..|..|..|:..:.|: .|.:||..:|...  ||:|:: ::||  .|..:|  :....||::|:.
Zfish   535 EGLDGVPFTVDVENNI-YCVKDYHTVFAPK--CASCNQPILPAQGSEETIRVVSMDKDYHVDCYH 596

  Fly   184 CQQCNHRFC--VGDRFYLCENKILCEYDYEERLVFASMANH--PMLKRHVSSL 232
            |:.|..:..  .|.|.|..|..:||...:..||. ..:|.|  |....||:.|
Zfish   597 CEDCGLQLNDEEGHRCYPLEGHLLCHRCHLHRLK-TPLAPHPPPSYPLHVTEL 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	16/53 (30%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	18/60 (30%)
wtip	NP_001116750.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..56
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	142..291
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..327
		LIM1_Ajuba_like	439..492	CDD:188738	10/60 (17%)
		LIM2_Ajuba_like	504..556	CDD:188741	16/53 (30%)
		LIM3_Ajuba_like	564..625	CDD:188822	18/60 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910