DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and pxnb

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_021334029.1	Gene:	pxnb / 565130	ZFINID:	ZDB-GENE-130530-697	Length:	1197	Species:	Danio rerio

Alignment Length:	147	Identity:	42/147 - (28%)
Similarity:	67/147 - (45%)	Gaps:	9/147 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNT 153
            |..|..|...|.|: ::.|||..||.:...|..|....|..|  .:.|.....|::||..||...
Zfish  1020 SPRCYYCNGPILDK-VVTALDRTWHPEHFFCAQCGAFFGPEG--FHEKDGKAYCRKDYFDLFAPK 1081

  Fly   154 GYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERL-VFA 217
              |..|::.|  .|..:.|.::::|.|||.|::|...| |...|:..:.:..||..|..|. ...
Zfish  1082 --CGGCARAI--LENYISALSSLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHARRGSLC 1141

  Fly   218 SMANHPMLKRHVSSLGQ 234
            |....|:..|.::::|:
Zfish  1142 SGCQKPITGRCITAMGK 1158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	15/53 (28%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	16/53 (30%)
pxnb	XP_021334029.1	Paxillin	96..272	CDD:308898
		Atrophin-1	<178..684	CDD:331285
		LIM1_Paxillin_like	964..1016	CDD:259830
		LIM2_Paxillin_like	1023..1074	CDD:188723	15/53 (28%)
		LIM3_Paxillin_like	1082..1134	CDD:188724	16/54 (30%)
		LIM4_Paxillin	1141..1192	CDD:188795	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920