DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and Pdlim5

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_006501801.1	Gene:	Pdlim5 / 56376	MGIID:	1927489	Length:	734	Species:	Mus musculus

Alignment Length:	279	Identity:	60/279 - (21%)
Similarity:	97/279 - (34%)	Gaps:	67/279 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GLVGLSSNQQQQQQQQSQQSNAGMNSG------GQNNGPNPN---------GNGNVVNVVNSGGA 61
            |...||:::..:....|:.|.||:.|.      |..:..:|:         ..|.:.|...|.|.
Mouse   463 GASPLSASEGPESPGSSRPSVAGLRSAAAFKPVGSTSVKSPSWQRPNQAAPSTGRISNNARSSGT 527

  Fly    62 GG--GNNGNGNVQSIAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDC 124
            |.  |.....:..::...|.:......  :.:||.|.:.|:..:|: ||...||.:...|..|..
Mouse   528 GASVGPPQPSDQDTLVQRAEHIPAGKR--TPMCAHCNQVIRGPFLV-ALGKSWHPEEFNCAHCKN 589

  Fly   125 RLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQC-- 187
            .:..:| .:..||.| .|:..|.:.|...  |..|.:.|  ...|:.|....:|:.||.|..|
Mouse   590 TMAYIG-FVEEKGAL-YCELCYEKFFAPE--CGRCQRKI--LGEVINALKQTWHVSCFVCVACGK 648

  Fly   188 ---NHRFCVGDRFYLCENKIL---------CEYDYE---------------------------ER 213
               |:.|.:.|....||....         ||:..|                           |.
Mouse   649 PIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEG 713

  Fly   214 LVFASMANHPMLKRHVSSL 232
            ..|.|..:.|:.|:|..|:
Mouse   714 QTFFSKKDKPLCKKHAHSV 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	16/53 (30%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	17/67 (25%)
Pdlim5	XP_006501801.1	PDZ_signaling	10..82	CDD:238492
		PHA03307	150..>540	CDD:223039	16/76 (21%)
		DUF4749	214..315	CDD:374237
		LIM1_ENH	558..609	CDD:188837	16/53 (30%)
		LIM2_ENH	617..668	CDD:188841	15/52 (29%)
		LIM3_ENH	676..730	CDD:188843	9/53 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910