DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and lpxn

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_689239.4	Gene:	lpxn / 560743	ZFINID:	ZDB-GENE-081105-159	Length:	405	Species:	Danio rerio

Alignment Length:	249	Identity:	58/249 - (23%)
Similarity:	102/249 - (40%)	Gaps:	48/249 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMTMDITKTEPGLVGLSSNQ--------QQQQQQQSQQSNAGMNSGGQNNGPNPNGNGNVVNVVN 57
            ::.:|:..:||   ..|||.        :.:..:::.:|.:|...|.:.....|      ::...
Zfish    86 LLGLDLEVSEP---APSSNPPPLARKSIKAKTTEETGESGSGRQEGDRKPQHPP------LSEKF 141

  Fly    58 SGGAGGGNNGNGNVQS------IAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDC 116
            |.|....::..|::.|      :..||..:          ||.|||.|..: ::.||..:||.:.
Zfish   142 SKGVDAIDDLLGSLSSDMEKMGVRTAAKGH----------CASCGKCIAGK-MITALGQVWHPEH 195

  Fly   117 LKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLEC 181
            ..|..|...||..|  .:.:.....|::||.:||  :..||.|..  |..:.::.|....:|.|.
Zfish   196 FVCSACREELGTCG--FFERDGKPYCEKDYQKLF--SPRCAYCKG--PITQNILTAMDQTWHPEH 254

  Fly   182 FACQQCNHRFCVGDRFYL-CENKILCEYDYEERLVFA---SMANHPMLKRHVSS 231
            |.|..|...|  |...|| .:.|..|..|:  ..:||   |....|:.:.::|:
Zfish   255 FFCCHCGDLF--GPEGYLERDGKPYCSRDF--YCLFAPKCSGCGEPVKENYLSA 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	16/53 (30%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	16/54 (30%)
lpxn	XP_689239.4	LIM1_Paxillin_like	172..224	CDD:259830	17/54 (31%)
		LIM2_Leupaxin	231..282	CDD:188792	16/54 (30%)
		LIM3_Leupaxin	290..342	CDD:188794	3/15 (20%)
		LIM4_Leupaxin	349..400	CDD:188796
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010