DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and lims2

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_021334342.1	Gene:	lims2 / 553696	ZFINID:	ZDB-GENE-050522-56	Length:	378	Species:	Danio rerio

Alignment Length:	146	Identity:	40/146 - (27%)
Similarity:	68/146 - (46%)	Gaps:	21/146 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 GSQLCAGCGKHIQDRYLLRALDMLWHED---CLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRL 149
            |..:|..|.:.::.| ::.|:...||.:   |:|     |....:|...|.:..|..|:..|.:|
Zfish   235 GVPICGACRRPVEGR-VVNAMGKQWHVEHFVCVK-----CEKPFLGHRHYERKGLAYCETHYNQL 293

  Fly   150 FGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERL 214
            ||:.  |..|::||..  .|:.|....:.:.||:|..|..|..:.|:|...:.|.:|::.||.
Zfish   294 FGDV--CFQCNRVIEG--DVVSALNKAWCVRCFSCSTCTSRLTLKDKFVEIDLKPVCKHCYER-- 352

  Fly   215 VFASMANHPMLKRHVS 230
                |.:.  |||.:|
Zfish   353 ----MPDE--LKRRLS 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	13/56 (23%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	15/53 (28%)
lims2	XP_021334342.1	LIM1_PINCH	57..115	CDD:188717
		LIM2_PINCH	118..169	CDD:188718
		LIM3_PINCH	182..231	CDD:188719
		LIM4_PINCH	237..290	CDD:188720	13/58 (22%)
		LIM5_PINCH	298..351	CDD:188721	15/54 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920