DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and lhx8

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_012816489.1	Gene:	lhx8 / 548653	XenbaseID:	XB-GENE-494997	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	155	Identity:	60/155 - (38%)
Similarity:	79/155 - (50%)	Gaps:	11/155 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 NNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLF 150
            |.|..:|:.||..|.|:|||:..|:.||..||.|..|...||. .::.|.|...:.||.||.|.:
Frog    98 NQGKSVCSNCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIYCKLDYFRRY 161

  Fly   151 GNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLV 215
            |..  |:.|.:.|.|.:.|.||:.|||||.||||..|..:...|:.|.|.|.|:||...|:..|
Frog   162 GTR--CSRCGRHIHATDWVRRAKGNVYHLACFACYSCKRQLSTGEEFALVEEKVLCRVHYDCML- 223

  Fly   216 FASMANHPMLKRHVSSLGQGSPTGA 240
                   ..|||.|.:..:.|..||
Frog   224 -------DNLKRAVENGNRVSVEGA 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	21/53 (40%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	24/53 (45%)
lhx8	XP_012816489.1	LIM1_Lhx7_Lhx8	103..158	CDD:188767	22/55 (40%)
		LIM2_Lhx7_Lhx8	165..219	CDD:188769	24/53 (45%)
		Homeobox	258..311	CDD:365835
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910