DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and PAX7

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_002575.1	Gene:	PAX7 / 5081	HGNCID:	8621	Length:	520	Species:	Homo sapiens

Alignment Length:	150	Identity:	33/150 - (22%)
Similarity:	56/150 - (37%)	Gaps:	25/150 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 SSLGQGSPTGAAGAQNTAGGLLGGGPGGGNVNGVGMVNGPRTPGDHNN---NNNGPQTPTGGGSP 291
            |::.||....||.|.:|:...  |.....:......:| |..|.:|.|   |...||..:..|:|
Human   332 STMHQGGLAAAAAAADTSSAY--GARHSFSSYSDSFMN-PAAPSNHMNPVSNGLSPQVMSILGNP 393

  Fly   292 FAAAAAAAA--AAAHMKNQLGASSXNKALGMGAAGAVVPGSGVGAGVGVGVGAASQQF----YSG 350
            .|......|  :.:.:...|.::: ..|.....|.::.||..:         ..||.:    ||.
Human   394 SAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSL---------PTSQAYCPPTYST 449

  Fly   351 FGLQHQ----HQHQQHHQQQ 366
            .|....    :|:.|:.|.:
Human   450 TGYSVDPVAGYQYGQYGQSE 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776
PAX7	NP_002575.1	paired box domain	34..164
		PAX	34..163	CDD:238076
		octapeptide	86..93
		paired homeodomain	217..275
		Homeobox	220..273	CDD:278475
		Pax7	347..385	CDD:289156	8/40 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..409		4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910