DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and PAX3

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_852124.1	Gene:	PAX3 / 5077	HGNCID:	8617	Length:	505	Species:	Homo sapiens

Alignment Length:	81	Identity:	19/81 - (23%)
Similarity:	28/81 - (34%)	Gaps:	25/81 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 PTGAAGAQNTAGGLLGGGPGGGNVNGVGMVNGPRTPGDHNNNNNGPQTP---------TGGGSPF 292
            |:|.:...|...|           ||:    .|:..|...|:...|..|         |||..|.
Human   373 PSGPSNPMNPTIG-----------NGL----SPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPT 422

  Fly   293 AAAAAAAAAAA-HMKN 307
            ...:|:.:... |||:
Human   423 TTVSASCSQRLDHMKS 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776
PAX3	NP_852124.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		PAX	34..159	CDD:128645
		PAI subdomain. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00381	37..93
		RED subdomain. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00381	113..161
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	165..228
		Homeobox	222..276	CDD:395001
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..351
		Pax7	347..391	CDD:403540	6/32 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910