DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bx and lhx6a

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001004015.1	Gene:	lhx6a / 445565	ZFINID:	ZDB-GENE-041025-1	Length:	375	Species:	Danio rerio

Alignment Length:	227	Identity:	71/227 - (31%)
Similarity:	98/227 - (43%)	Gaps:	36/227 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PGLVGLSSNQQQQQQQQS--QQSNAGMNSGGQNNGPNPNGNGNVVNVVNSGGAGGGNNGNGNVQS 73
            ||.......|..|...||  :...:.|......:.|:|                      .:..|
Zfish    36 PGASRCVDGQHGQAMSQSDGESHRSNMEKDDTRSSPSP----------------------PSTPS 78

  Fly    74 IAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGN 138
            |.:..:..::..:.|..:||.||..|.|||||:..:::||..||:|..|...|.: .|:.|.|..
Zfish    79 ICSPTSTASSVPSTGKNVCASCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQ-HSSCYIKNK 142

  Fly   139 LMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENK 203
            .:.||.||...||..  ||.|.:.|.|.:.|.|||.|.|||.||||..|..:...|:.|.|.|.|
Zfish   143 EIFCKMDYFSRFGTK--CARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEK 205

  Fly   204 ILCEYDYEERLVFASMANHPMLKRHVSSLGQG 235
            :||...|:      :|..:  |||...| |.|
Zfish   206 VLCRIHYD------TMVEN--LKRAAES-GSG 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	22/53 (42%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	25/53 (47%)
lhx6a	NP_001004015.1	LIM1_Lhx6	97..150	CDD:188766	22/53 (42%)
		LIM2_Lhx6	158..212	CDD:188768	25/53 (47%)
		Homeobox	250..302	CDD:278475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910