DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and ct

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster

Alignment Length:	443	Identity:	106/443 - (23%)
Similarity:	146/443 - (32%)	Gaps:	141/443 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TKTEPGLVGLSSNQQQQQQQQ-------------------------------SQQSNAGMNSGGQ 40
            |:|||     |:..|||.|||                               |:::|.|.|...|
  Fly   312 TRTEP-----SATTQQQHQQQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSRKNNNGGNESEQ 371

  Fly    41 ------------NNGPNPNGNGNVVNVVNSGGAGGGNNGNGNVQSIAAAANNNNNNNNNGSQLCA 93
                        ||..|.:.|.|..|...|......||.:.:..|......||||||...:.|.|
  Fly   372 HVASSAEDDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRKKKNNNNNNGQPAVLLA 436

  Fly    94 GCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGN------ 152
            ...|.|  :.||..|..|..::       ...|.::..   .:.:|.:.::..:||...
  Fly   437 AKDKEI--KALLDELQRLRAQE-------QTHLVQIQR---LEEHLEVKRQHIIRLEARLDKQQI 489

  Fly   153 -------TGYCAACS--------------KVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDR 196
                   |...||.|              |:..|.|..|.|.:|                  .|.
  Fly   490 NEALAEATALSAAASTNNNNNSQSSDNNKKLNTAAERPMDASSN------------------ADL 536

  Fly   197 FYLCENKILCEYDYEER----LVFASMA-NHPMLKRHVSSLGQGSPTGAAGAQNTAGGLLGGGPG 256
            ....:..:..|.|.|:.    ||.:..| :.|....|.....:.....|..|..|
  Fly   537 PESTKAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHHDDDEDEDEDREAVNATTT---------- 591

  Fly   257 GGNVNGVGMVNGPRTPGDHNNNNNGPQTPTGGGSPFAAAAAAAAAAAHMKNQLGA--SSXNKALG 319
              :.|.:.:.....:|.|.|..:  |.:....    |||||||||.|:..|:..|  ....|||
  Fly   592 --DSNELKIKKEQHSPLDLNVLS--PNSAIAA----AAAAAAAAACANDPNKFQALLIERTKAL- 647

  Fly   320 MGAAGAVVPGSGVGAGVGVGVGAASQQFYSGFGLQHQHQH-QQHHQQQQQQQQ 371
              ||.|:  .:|....:........||.:     |.|||| |||||||...||
  Fly   648 --AAEAL--KNGASDALSEDAHHQQQQHH-----QQQHQHQQQHHQQQHLHQQ 691

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	9/53 (17%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	11/67 (16%)
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910